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Effect of dietary polyunsaturated fatty acids on gut mucosal mast cells in calves

Published online by Cambridge University Press:  20 November 2017

K.N. Muturi ,
J. Struthers ,
J. R. Scaife ,
A. Mackellar ,
J.F. Huntley  and
R.L. Coop
K.N. Muturi*
Affiliation:
Department of Agriculture & Forestry, School of Biological Sciences, University of Aberdeen, Hilton Campus, Block M, Hilton Place, Aberdeen AB24 4FA. Scotland, UK
J. Struthers
Affiliation:
Department of Agriculture & Forestry, School of Biological Sciences, University of Aberdeen, Hilton Campus, Block M, Hilton Place, Aberdeen AB24 4FA. Scotland, UK
J. R. Scaife
Affiliation:
Department of Agriculture & Forestry, School of Biological Sciences, University of Aberdeen, Hilton Campus, Block M, Hilton Place, Aberdeen AB24 4FA. Scotland, UK
A. Mackellar
Affiliation:
Moredun Research Institute, Pentlands Science Park, Pencuik, Edinburgh, EH26 0PZ U.K.
J.F. Huntley
Affiliation:
Moredun Research Institute, Pentlands Science Park, Pencuik, Edinburgh, EH26 0PZ U.K.
R.L. Coop
Affiliation:
Moredun Research Institute, Pentlands Science Park, Pencuik, Edinburgh, EH26 0PZ U.K.
*
[email protected]
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Extract

Polyunsaturated fatty acids (PUFA), especially the n-3 and n-6 families are dietary compounds with significant immunomodulatory potential. Mechanisms proposed to explain their impact on immune function include (1) direct effects on leukocyte and epithelial cell membrane function, (2) the regulation of expression of immune genes and their products and (3) eicosanoid-mediated mechanisms (Hwang, 2000). Eicosanoids are immune effector molecules which have important roles in the regulation of immune and inflammatory responses (Calder, 2001). The aim of this experiment was to establish the extent to which supplementation of pre-ruminant calves with an n-6 or n-3 PUFA source may influence mucosal mast cell numbers in the abomasum (ABO), duodenum (DD) and terminal ileum (TI).

Type
Theatre Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2004 , 2004 , pp. 69
Copyright
Copyright © The British Society of Animal Science 2004

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References

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