Artificial rearing is a common practice for rearing calves from the dairy herd destined for beef production or as replacements for the dairy or suckler herds. One of the major expenses with calf rearing is the cost of the milk. Hence emphasis is placed on early weaning of the calf at 5-7 weeks old and encouraging concentrate intake. With increasing consumer concern over the use of antibiotics in feed, there is greater focus on the use of probiotics or yeast cultures to enhance calf performance. Yeast culture is a fermentation product resulting from the inoculation of grains with Saccharomyces cerevisiae and its growth media. This yeast culture mash is incubated and dried in a manner that preserves all the metabolites and the fermenting activity of the yeast. The objective of this study was to determine the effect of feeding a yeast culture (YC) on the performance of early-weaned beef calves.