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Effect of naturally occurring and synthetic androgens on growth, body composition and muscle glucocorticoid receptors in wether lambs

Published online by Cambridge University Press:  21 November 2017

H. Galbraith
Affiliation:
School of Agriculture, 581 King Street, Aberdeen AB9 1UD
A.D. Berry
Affiliation:
School of Agriculture, 581 King Street, Aberdeen AB9 1UD
G.D. Henderson
Affiliation:
School of Agriculture, 581 King Street, Aberdeen AB9 1UD
C.S. Jessiman
Affiliation:
School of Agriculture, 581 King Street, Aberdeen AB9 1UD
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Extract

Naturally-occurring androgens such as testosterone are important in regulating growth in entire male animals (e.g. Galbraith & Topps, 1981). Synthetic steroids with androgenic properties when given exogenously are also known to alter growth of sheep and cattle. Knowledge on the effects of these androgens on body composition and on their mode of action is Inadequate. The major objective of this study was to compare their effects on growth performance and body composition and to relate the responses obtained to changes in certain characteristics of the endocrine system and glucocorticoid receptors in muscle. The steroids used were testosterone (naturally occurring), trenbolone acetate (TBA) (synthetic compound) and nandrolone (19 nor-testosterone - produced synthetically and considered not to occur naturally in castrate male sheep).

Type
New Approaches to Growth Manipulation
Copyright
Copyright © The British Society of Animal Production 1986

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References

Galbralth, H. & Topps, J.H. (1981). Nutr. Abtrs. Rev. Ser (B), 51, 521.Google Scholar
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Sharpe, P.M., Buttery, P.J. & Haynes, N.B. (1984). Can. J. Anim. Sci. 64(Suppl.) 310.CrossRefGoogle Scholar