Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-22T05:53:22.887Z Has data issue: false hasContentIssue false

Prehospital Management and Fluid Resuscitation in Hypotensive Trauma Patients Admitted to Karolinska University Hospital in Stockholm

Published online by Cambridge University Press:  28 June 2012

Peep Talving*
Affiliation:
Karolinska Trauma Center Department of Surgery Karolinska University Hospital Stockholm, Sweden
Joakim Pålstedt
Affiliation:
Karolinska Trauma Center Department of Surgery Karolinska University Hospital Stockholm, Sweden
Louis Riddez
Affiliation:
Karolinska Trauma Center Department of Surgery Karolinska University Hospital Stockholm, Sweden
*
Department of Surgery Karolinska University Hospital 171 76 Stockholm, Sweden E-mail: [email protected]

Abstract

Introduction:

Few previous studies have been conducted on the prehospital management of hypotensive trauma patients in Stockholm County. The aim of this study was to describe the prehospital management of hypotensive trauma patients admitted to the largest trauma center in Sweden, and to assess whether prehospital trauma life support (PHTLS) guidelines have been implemented regarding prehospital time intervals and fluid therapy. In addition, the effects of the age, type of injury, injury severity, prehospital time interval, blood pressure, and fluid therapy on outcome were investigated.

Methods:

This is a retrospective, descriptive study on consecutive, hypotensivetrauma patients (systolic blood pressure ≤90 mmHg on the scene of injury) admitted to Karolinska University Hospital in Stockholm, Sweden, during 2001–2003. The reported values are medians with interquartile ranges. Basic demographics, prehospital time intervals and interventions, injury severity scores (ISS), type and volumes of prehospital fluid resuscitation, and 30-day mortality were abstracted. The effects of the patient's age, gender, prehospital time interval, type of injury, injury severity, on-scene and emergency department blood pressure, and resuscitation fluid volumes on mortality were analyzed using the exact logistic regression model.

Results:

In 102 (71 male) adult patients (age ≥15 years) recruited, the median age was 35.5 years (range: 27–55 years) and 77 patients (75%) had suffered blunt injury. The predominant trauma mechanisms were falls between levels (24%) and motor vehicle crashes (22%) with an ISS of 28.5 (range: 16–50). The on-scene time interval was 19 minutes (range: 12–24 minutes). Fluid therapy was initiated at the scene of injury in the majority of patients (73%) regardless of the type of injury (77 blunt [75%] / 25 penetrating [25%]) or injury severity (ISS: 0–20; 21–40; 41–75). Age (odds ratio (OR) = 1.04), male gender (OR = 3.2), ISS 21–40 (OR = 13.6), and ISS >40 (OR = 43.6) were the significant factors affecting outcome in the exact logistic regression analysis.

Conclusion:

The time interval at the scene of injury exceeded PHTLS guidelines. The vast majority of the hypotensive trauma patients were fluid-resuscitated on-scene regardless of the type, mechanism, or severity of injury. A predefined fluid resuscitation regimen is not employed in hypotensive trauma victims with different types of injuries. The outcome was worsened by male gender, progressive age, and ISS >20 in the exact multiple regression analysis.

Type
Research Article
Copyright
Copyright © World Association for Disaster and Emergency Medicine 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Sauaia, A, Moore, FA, Moore, EE et al: Epidemiology of trauma deaths: A reassessment. J Trauma 1995;38(2):185193.CrossRefGoogle ScholarPubMed
2Acosta, JA, Yang, JC, Winchell, RJ et al: Lethal injuries and time to death in a level I trauma center. J Am Coll Surg 1998;186(5):528533.CrossRefGoogle ScholarPubMed
3Ali, J, Adam, RU, Gana, TJ et al: Effect of the Prehospital Trauma Life Support Program (PHTLS) on prehospital trauma care. J Trauma 1997; 42(5):786790.Google ScholarPubMed
4Boyington, T, Williams, D: Pre-hospital care—Current concepts. Accid Emerg Nurs 1995;3(1):4547.CrossRefGoogle ScholarPubMed
5Arreola-Risa, C, Mock, CN, Lojero-Wheatly, L et al: Low-cost improvements in prehospital trauma care in a Latin American city. J Trauma 2000; 48(1):119124.CrossRefGoogle Scholar
6McSwain, NE, Frame, S, Paturas, JL et al (eds): PHTLS—Basic and Advanced Prehospital Trauma Life Support. 4th ed, St. Louis: Mosby-Year Book, Inc., 1999.Google Scholar
7McSwain, NE, Frame, S, Paturas, JL et al (eds): PHTLS—Basic and Advanced Prehospital Trauma Life Support. 4th ed, St. Louis: Mosby-Year Book, Inc., 1999. pp 38,152–153,304.Google Scholar
8American College of Surgeons Committee on Trauma: Advanced Trauma Life Support ® for Doctors: ATLS. 7th ed., Chicago, IL., USA, 2004.Google Scholar
9Baker, SP, O'Neill, B, Haddon, W Jr, Long, WB: The Injury Severity Score: A method for describing patients with multiple injuries and evaluating emergency care. J Trauma 1974:14;187196.CrossRefGoogle ScholarPubMed
10Dick, WF, Baskett, PJ: Recommendation for uniform reporting of data following major trauma–The Utstein style: A report of working party of the International Trauma Anaesthesia and Critical Care Society (ITACCS). Resuscitation 1999;42:81100.Google Scholar
11Champion, HR, Copes, WS, Sacco, WJ et al: The Major Trauma Outcome Study: Establishing national norms for trauma care. J Trauma 1990;30(11): 13561365.CrossRefGoogle ScholarPubMed
12Knudson, MM, Lieberman, J, Morris, JA Jr et al: Mortality factors in geriatric blunt trauma patients. Arch Surg 1994;129(4);448453.CrossRefGoogle ScholarPubMed
13Jones, JM, Maryosh, J, Johnstone, S, Templeton, J: A multivariate analysis of factors related to the mortality of blunt trauma admissions to the North Staffordshire Hospital Centre. J Trauma 1995;38(1):118122.CrossRefGoogle Scholar
14Sampalis, JS, Lavoie, A, Salas, M et al: Determinants of on-scene time in injured patients treated by physicians at the site. Prehosp Disast Med 1994;9(3):178188.CrossRefGoogle ScholarPubMed
15Goodacre, SW, Gray, A, McGowan, A: On-scene times for trauma patients in West Yorkshire. J Accid Emerg Med 1997;14(5):283285.CrossRefGoogle ScholarPubMed
16Wik, L, Hansen, TB, Kjensli, K, Steen, PA: Rapid extrication from a car wreck. Injury 2004;35(8):739745.CrossRefGoogle ScholarPubMed
17Demetriades, D, Chan, L, Cornwell, E et al: Paramedic vs. private transportation of trauma patients: Effect on outcome. Arch Surg 1996;131(2): 133138.Google Scholar
18Feero, S, Hedges, JR, Simmons, E, Irwin, L: Does out-of-hospital EMS time affect trauma survival? Am J Emerg Med 1995;13(2):133135.CrossRefGoogle ScholarPubMed
19O'Gorman, M, Trabulsy, P, Pilcher, DB: Zero-time prehospital IV. J Trauma 1989;29(1):8486.CrossRefGoogle Scholar
20Jones, SE, Nesper, TP, Alcouloumre E: Prehospital intravenous line placement: A prospective study. Ann Emerg Med 1989;18(3):244246.CrossRefGoogle ScholarPubMed
21MacDonald, RL, Schwartz, ML, Mirich, D: Diagnosis of cervical spine injury in motor vehicle crash victims: How many x-rays are enough? J Trauma 1990;30:392397.CrossRefGoogle Scholar
22Chiu, WC, Haan, JH, Cushing, BM et al: Ligamentous injuries of the cervical spine in unreliable blunt trauma patients: Incidence, evaluation and outcome. J Trauma 2001;50:457463.CrossRefGoogle ScholarPubMed
23Demetriades, D, Charalambides, K, Chahwan, S et al: Nonskeletal cervical spine injuries: Epidemiology and diagnostic pitfalls. J Trauma 2000;48: 724727.CrossRefGoogle ScholarPubMed
24Wade, CE, Kramer, GC, Grady, JJ et al: Efficacy of hypertonic 7.5% saline and 6% dextran-70 in treating trauma: A meta-analysis of controlled clinical studies. Surgery 1997;122(3):609616.Google ScholarPubMed
25Wade, CE, Grady, JJ, Kramer, GC et al: Individual patient cohort analysis of the efficiacy of hypertonic saline/dextran in patients with traumatic brain injury and hypotension. J Trauma 1997:42;6165CrossRefGoogle Scholar
26Stern, SA, Zink, BJ, Mertz, M, Wang, X, Dronen, SC: Effect of initially limited resuscitation in a combined model of fluid-percussion brain injury and severe uncontrolled hemorrhagic shock. J Neurosurg 2000;93(2):305314.CrossRefGoogle Scholar
27Bickell, WH, Bruttig, SP, Millnarnow, GA et al: The detrimental effects of intravenous crystalloid after aortotomy in swine. Surgery 1991;110:529536.Google ScholarPubMed
28Stern, SA, Dronen, SC, Wang, X: Multiple resuscitation regimens in a near fatal porcine aortic injury hemorrhage model. Acad Emerg Med 1995;2: 8997.CrossRefGoogle Scholar
29Hatoum, OA, Bashenko, Y, Hirsch, M et al: Continuous fluid resuscitation and splenectomy for treatment of uncontrolled hemorrhagic shock after massive splenic injury. J Trauma 2002;52:253258.Google ScholarPubMed
30Riddez, L, Drobin, D, Sjostrand, F et al: Lower dose of hypertonic saline dextran reduces the risk of lethal rebleeding in uncontrolled hemorrhage. Shock 2002;17(5):377382.CrossRefGoogle ScholarPubMed
31Riddez, L, Hjelmqvist, H, Suneson, A, Hahn, RG: Short-term crystalloid fluid resuscitation in uncontrolled intra-abdominal bleeding in swine. Prehosp Disast Med 1999;14(2):8792.CrossRefGoogle ScholarPubMed
32Cwinn, AA, Pons, PT, Moore, EE et al: Prehospital advanced trauma life support for critical blunt trauma victims. Ann Emerg Med 1987;16(4):399403.CrossRefGoogle ScholarPubMed
33Bickell, WH, Wall, MJ Jr, Pepe, PE et al: Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries. N Engl J Med 1994;331(17):11051109.CrossRefGoogle ScholarPubMed
34Donovan, PJ, Cline, DM, Whitley, TW et al: Prehospital care by EMTs and EMT-Is in a rural setting: Prolongation of scene times by ALS procedures. Ann Emerg Med 1989;18(5):495500.CrossRefGoogle Scholar
35Dutton, RP, Mackenzie, CF, Scalea, TM: Hypotensive resuscitation during active hemorrhage: Impact on in-hospital mortality. J Trauma 2002;52(6): 11411146.CrossRefGoogle ScholarPubMed