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Accuracy of National Early Warning Score 2 (NEWS2) in Prehospital Triage on In-Hospital Early Mortality: A Multi-Center Observational Prospective Cohort Study

Published online by Cambridge University Press:  25 October 2019

Francisco Martín-Rodríguez
Affiliation:
Advanced Clinical Simulation Center, Faculty of Medicine, Universidad de Valladolid, Valladolid, Spain Advanced Medical Life Support, Gerencia de Emergencias Sanitarias de Castilla y León, Spain
Raúl López-Izquierdo*
Affiliation:
Advanced Clinical Simulation Center, Faculty of Medicine, Universidad de Valladolid, Valladolid, Spain Emergency Department, Hospital Universitario Rio Hortega, Valladolid, Spain
Carlos del Pozo Vegas
Affiliation:
Emergency Department, Hospital Clínico Universitario, Valladolid, Spain
Juan F. Delgado Benito
Affiliation:
Advanced Medical Life Support, Gerencia de Emergencias Sanitarias de Castilla y León, Spain
Virginia Carbajosa Rodríguez
Affiliation:
Emergency Department, Hospital Universitario Rio Hortega, Valladolid, Spain
María N. Diego Rasilla
Affiliation:
Advanced Medical Life Support, Gerencia de Emergencias Sanitarias de Castilla y León, Spain
José Luis Martín Conty
Affiliation:
Faculty of Occupational Therapy, Speech Therapy, and Nursing, Castilla la Mancha University, Talavera de la Reina, Toledo, Spain
Agustín Mayo Iscar
Affiliation:
Department of Statistics and Operative Research & IMUVA, Faculty of Medicine, Universidad de Valladolid, Valladolid, Spain
Santiago Otero de la Torre
Affiliation:
Advanced Medical Life Support, Gerencia de Emergencias Sanitarias de Castilla y León, Spain
Violante Méndez Martín
Affiliation:
Emergency Department, Complejo Asistencial de Salamanca, Salamanca, Spain
Miguel A. Castro Villamor
Affiliation:
Advanced Clinical Simulation Center, Faculty of Medicine, Universidad de Valladolid, Valladolid, Spain
*
Correspondence: Raúl López-Izquierdo, PhD Emergency Department Hospital Universitario Rio Hortega C/ Dulzaina 2. 47012-Valladolid, Spain E-mail: [email protected]

Abstract

Introduction:

In cases of mass-casualty incidents (MCIs), triage represents a fundamental tool for the management of and assistance to the wounded, which helps discriminate not only the priority of attention, but also the priority of referral to the most suitable center.

Hypothesis/Problem:

The objective of this study was to evaluate the capacity of different prehospital triage systems based on physiological parameters (Shock Index [SI], Glasgow-Age-Pressure Score [GAP], Revised Trauma Score [RTS], and National Early Warning Score 2 [NEWS2]) to predict early mortality (within 48 hours) from the index event for use in MCIs.

Methods:

This was a longitudinal prospective observational multi-center study on patients who were attended by Advanced Life Support (ALS) units and transferred to the emergency department (ED) of their reference hospital. Collected were: demographic, physiological, and clinical variables; main diagnosis; and data on early mortality. The main outcome variable was mortality from any cause within 48 hours.

Results:

From April 1, 2018 through February 28, 2019, a total of 1,288 patients were included in this study. Of these, 262 (20.3%) participants required assistance for trauma and injuries by external agents. Early mortality within the first 48 hours due to any cause affected 69 patients (5.4%). The system with the best predictive capacity was the NEWS2 with an area under the curve (AUC) of 0.891 (95% CI, 0.84-0.94); a sensitivity of 79.7% (95% CI, 68.8-87.5); and a specificity of 84.5% (95% CI, 82.4-86.4) for a cut-off point of nine points, with a positive likelihood ratio of 5.14 (95% CI, 4.31-6.14) and a negative predictive value of 98.7% (95% CI, 97.8-99.2).

Conclusion:

Prehospital scores of the NEWS2 are easy to obtain and represent a reliable test, which make it an ideal system to help in the initial assessment of high-risk patients, and to determine their level of triage effectively and efficiently. The Prehospital Emergency Medical System (PhEMS) should evaluate the inclusion of the NEWS2 as a triage system, which is especially useful for the second triage (evacuation priority).

Type
Original Research
Copyright
© World Association for Disaster and Emergency Medicine 2019 

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Footnotes

(Note: The first and second authors contributed equally to this manuscript.)

References

Turner, CDA, Lockey, DJ, Rehn, M. Pre-hospital management of mass casualty civilian shootings: a systematic literature review. Crit Care. 2017;21(1):94.CrossRefGoogle ScholarPubMed
Lewis, AM, Sordo, S, Weireter, LJ, et al. Mass casualty incident management preparedness: a survey of the American College of Surgeons Committee on Trauma. Am Surg. 2016;82(12):12271231.Google ScholarPubMed
Silvestri, S, Field, A, Mangalat, N, et al. Comparison of START and SALT triage methodologies to reference standard definitions and to a field mass casualty simulation. Am J Disaster Med. 2017;12(1):2733.CrossRefGoogle ScholarPubMed
Jain, TN, Ragazzoni, L, Stryhn, H, Stratton, SJ, Della Corte, F. Comparison of the Sacco Triage Method versus START Triage using a virtual reality scenario in advance care paramedic students. CJEM. 2016;18(4):288292.CrossRefGoogle ScholarPubMed
Hart, A, Nammour, E, Mangolds, V, Broach, J. Intuitive versus algorithmic triage. Prehosp Disaster Med. 2018;33(4):355361.CrossRefGoogle ScholarPubMed
Arcos González, P, Castro Delgado, R, Cuartas Alvarez, T, et al. The development and features of the Spanish prehospital advanced triage method (META) for mass casualty incidents. Scand J Trauma Resusc Emerg Med. 2016;24:63.CrossRefGoogle ScholarPubMed
Curran-Sills, G, Franc, JM. A pilot study examining the speed and accuracy of triage for simulated disaster patients in an emergency department setting: comparison of a computerized version of Canadian Triage Acuity Scale (CTAS) and Simple Triage and Rapid Treatment (START) methods. CJEM. 2017;19(5):364371.CrossRefGoogle Scholar
Galvagno, SM, Massey, M, Bouzat, P, et al. Correlation between the Revised Trauma Score and Injury Severity Score: implications for prehospital trauma triage. Prehosp Emerg Care. 2019;23(2):263270.CrossRefGoogle ScholarPubMed
Sartorius, D, Le Manach, Y, David, JS, et al. Mechanism, Glasgow coma scale, age, and arterial pressure (MGAP): a new simple prehospital triage score to predict mortality in trauma patients. Crit Care Med. 2010;38(3):831837.CrossRefGoogle ScholarPubMed
Cassignol, A, Markarian, T, Cotte, J, et al. Evaluation and comparison of different prehospital triage scores of trauma patients on in-hospital mortality. Prehosp Emerg Care. 2019;23(4):543550.CrossRefGoogle ScholarPubMed
Najafi, Z, Abbaszadeh, A, Zakeri, H, Mirhaghi, A. Determination of mis-triage in trauma patients: a systematic review. Eur J Trauma Emerg Surg. 2019.CrossRefGoogle Scholar
Massalou, D, Ichai, C, Mariage, D, Baqué, P. Terrorist attack in Nice - the experience of general surgeons. J Visc Surg. 2019;156(1):1722.CrossRefGoogle ScholarPubMed
Wydo, SM, Seamon, MJ, Melanson, SW, Thomas, P, Bahner, DP, Stawicki, SP. Portable ultrasound in disaster triage: a focused review. Eur J Trauma Emerg Surg. 2016;42(2):151159.CrossRefGoogle ScholarPubMed
Shokoohi, H, Pourmand, A, Boniface, K, et al. The utility of point-of-care ultrasound in targeted automobile ramming mass casualty (TARMAC) attacks. Am J Emerg Med. 2018;36(8):14671471.CrossRefGoogle ScholarPubMed
Kost, GJ, Tran, NK, Tuntideelert, M, Kulrattanamaneeporn, S, Peungposop, N. Katrina, the tsunami, and point-of-care testing: optimizing rapid response diagnosis in disasters. Am J Clin Pathol. 2006;126(4):513520.CrossRefGoogle ScholarPubMed
Florkowski, C, Don-Wauchope, A, Gimenez, N, Rodriguez-Capote, K, Wils, J, Zemlin, A. Point-of-care testing (POCT) and evidence-based laboratory medicine (EBLM) - does it leverage any advantage in clinical decision making? Crit Rev Clin Lab Sci. 2017;54(7-8):471494.CrossRefGoogle ScholarPubMed
Léguillier, T, Jouffroy, R, Boisson, M, et al. Lactate POCT in mobile intensive care units for septic patients? A comparison of capillary blood method versus venous blood and plasma-based reference methods. Clin Biochem. 2018;55:914.CrossRefGoogle ScholarPubMed
Lewis, CT, Naumann, DN, Crombie, N, Midwinter, MJ. Prehospital point-of-care lactate following trauma: a systematic review. J Trauma Acute Care Surg. 2016;81(4):748755.CrossRefGoogle ScholarPubMed
Royal-College-of-Physicians. National Early Warning Score (NEWS) 2: Standardizing the Assessment of Acute-Illness Severity in the NHS. Updated Report of a Working Party. London, United Kingdom: RCP; 2017.Google Scholar
Silcock, DJ, Corfield, AR, Gowens, PA, Rooney, KD. Validation of the National Early Warning Score in the prehospital setting. Resuscitation. 2015;89:3135.CrossRefGoogle ScholarPubMed
Alam, N, Vegting, IL, Houben, E, et al. Exploring the performance of the National Early Warning Score (NEWS) in a European emergency department. Resuscitation. 2015;90:111115.CrossRefGoogle Scholar
Hoikka, M, Silfvast, T, Ala-Kokko, TI. Does the prehospital National Early Warning Score predict the short-term mortality of unselected emergency patients? Scand J Trauma Resusc Emerg Med. 2018;26(1):48.CrossRefGoogle ScholarPubMed
Gerry, S, Birks, J, Bonnici, T, Watkinson, PJ, Kirtley, S, Collins, GS. Early warning scores for detecting deterioration in adult hospital patients: a systematic review protocol. BMJ Open. 2017;7(12):e019268.CrossRefGoogle ScholarPubMed
Hoikka, M, Länkimäki, S, Silfvast, T, Ala-Kokko, TI. Medical priority dispatch codes-comparison with National Early Warning Score. Scand J Trauma Resusc Emerg Med. 2016;24(1):142.CrossRefGoogle ScholarPubMed
Abbott, TEF, Cron, N, Vaid, N, Ip, D, Torrance, HDT, Emmanuel, J. Prehospital National Early Warning Score (NEWS) is associated with in-hospital mortality and critical care unit admission: a cohort study. Ann Med Surg (Lond). 2018;27:1721.CrossRefGoogle Scholar
Downey, CL, Tahir, W, Randell, R, Brown, JM, Jayne, DG. Strengths and limitations of early warning scores: a systematic review and narrative synthesis. Int J Nurs Stud. 2017;76:106119.CrossRefGoogle ScholarPubMed
Shaw, J, Fothergill, RT, Clark, S, Moore, F. Can the prehospital National Early Warning Score identify patients most at risk from subsequent deterioration? Emerg Med J. 2017;34(8):533537.CrossRefGoogle ScholarPubMed
Williams, TA, Tohira, H, Finn, J, Perkins, GD, Ho, KM. The ability of early warning scores (EWS) to detect critical illness in the prehospital setting: a systematic review. Resuscitation. 2016;102:3543.CrossRefGoogle ScholarPubMed
Skitch, S, Tam, B, Xu, M, McInnis, L, Vu, A, Fox-Robichaud, A. Examining the utility of the Hamilton early warning scores (HEWS) at triage: retrospective pilot study in a Canadian emergency department. CJEM. 2018;20(2):266274.CrossRefGoogle Scholar
Kievlan, DR, Martin-Gill, C, Kahn, JM, et al. External validation of a prehospital risk score for critical illness. Crit Care. 2016;20(1):255.CrossRefGoogle ScholarPubMed
Churpek, MM, Yuen, TC, Winslow, C, et al. Multicenter development and validation of a risk stratification tool for ward patients. Am J Respir Crit Care Med. 2014;190(6):649655.CrossRefGoogle ScholarPubMed
Myint, PK, Sheng, S, Xian, Y, et al. Shock Index predicts patient-related clinical outcomes in stroke. J Am Heart Assoc. 2018;7(18):e007581.CrossRefGoogle ScholarPubMed
Pottecher, J, Ageron, FX, Fauché, C, et al. Prehospital shock index and pulse pressure/heart rate ratio to predict massive transfusion after severe trauma: retrospective analysis of a large regional trauma database. J Trauma Acute Care Surg. 2016;81(4):713722.CrossRefGoogle ScholarPubMed
Köksal, Ö, Torun, G, Ahun, E, Sığırlı, D, Güney, SB, Aydın, MO. The comparison of modified early warning score and Glasgow coma scale-age-systolic blood pressure scores in the assessment of nontraumatic critical patients in emergency department. Niger J Clin Pract. 2016;19(6):761765.CrossRefGoogle ScholarPubMed
Baghi, I, Shokrgozar, L, Herfatkar, MR, Nezhad Ehsan, K, Mohtasham Amiri, Z. Mechanism of injury, Glasgow Coma Scale, age, and systolic blood pressure: a new trauma scoring system to predict mortality in trauma patients. Trauma Mon. 2015;20(3):e2447.Google ScholarPubMed
Jeong, JH, Park, YJ, Kim, DH, et al. The new trauma score (NTS): a modification of the revised trauma score for better trauma mortality prediction. BMC Surg. 2017;17(1):77.CrossRefGoogle ScholarPubMed
Manoochehry, S, Vafabin, M, Bitaraf, S, Amiri, A. A comparison between the ability of Revised Trauma Score and Kampala Trauma Score in predicting mortality; a meta-analysis. Arch Acad Emerg Med. 2019;7(1):e6.Google ScholarPubMed
Patel, R, Nugawela, MD, Edwards, HB, et al. Can early warning scores identify deteriorating patients in pre-hospital settings? A systematic review. Resuscitation. 2018;132:101111.CrossRefGoogle ScholarPubMed
Alam, N, Hobbelink, EL, van Tienhoven, AJ, van de Ven, PM, Jansma, EP, Nanayakkara, PWB. The impact of the use of the Early Warning Score (EWS) on patient outcomes: a systematic review. Resuscitation. 2014;85(5):587594.CrossRefGoogle ScholarPubMed
van Rein, EAJ, Houwert, RM, Gunning, AC, Lichtveld, RA, Leenen, LPH, van Heijl, M. Accuracy of prehospital triage protocols in selecting severely injured patients: a systematic review. J Trauma Acute Care Surg. 2017;83(2):328339.CrossRefGoogle ScholarPubMed
Parikh, PP, Parikh, P, Guthrie, B, et al. Impact of triage guidelines on prehospital triage: comparison of guidelines with a statistical model. J Surg Res. 2017;220:255260.CrossRefGoogle ScholarPubMed
van Rein, EAJ, van der Sluijs, R, Houwert, RM, et al. Effectiveness of prehospital trauma triage systems in selecting severely injured patients: is comparative analysis possible? Am J Emerg Med. 2018;36(6):10601069.CrossRefGoogle ScholarPubMed
van Rein, EAJ, van der Sluijs, R, Raaijmaakers, AMR, Leenen, LPH, van Heijl, M. Compliance to prehospital trauma triage protocols worldwide: a systematic review. Injury. 2018;49(8):13731380.CrossRefGoogle ScholarPubMed
Strnad, M, Lesjak, VB, Vujanović, V, Pelcl, T, Križmarić, M. Predictors of mortality and prehospital monitoring limitations in blunt trauma patients. Biomed Res Int. 2015;2015:98340.CrossRefGoogle ScholarPubMed
Ebker-White, A, Bein, KJ, Dinh, MM. Extending the Sydney Triage to Admission Risk Tool (START+) to predict discharges and short stay admissions. Emerg Med J. 2108;35(8):471476.CrossRefGoogle Scholar