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Effect of Colloid Oncotic Pressure on Closing Lung Volumes in Dogs

Published online by Cambridge University Press:  28 June 2012

George Havasi ,
Jonas Gintautas  and
Ilona Havasi
George Havasi
Affiliation:
From the Department of Anesthesiology, Texas Technical University Health Science Center, Lubbock, Texas, USA.
Jonas Gintautas
Affiliation:
From the Department of Anesthesiology, Texas Technical University Health Science Center, Lubbock, Texas, USA.
Ilona Havasi
Affiliation:
From the Department of Anesthesiology, Texas Technical University Health Science Center, Lubbock, Texas, USA.
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Extract

The question of whether colloids are better than crystalloid solutions for resuscitation of hypovolemic patients remains to be answered.

The purpose of this study was to investigate how the closing lung volume is affected by a reduction of colloid oncotic pressure.

We measured closing lung volumes of anesthetized dogs in the presence of undisturbed serum proteins (COP= 18.9–22.1 mmHg). Following these determinations, we reduced the colloid oncotic pressure to 10.9–12.9 mmHg by administration of 50 ml/kg of 5% dextrose solution. Closing lung volumes were evaluated repeatedly from 10 to 90 minutes following the completion of infusion.

Type
Part II: Clinical Care Topics
Information
Prehospital and Disaster Medicine , Volume 1 , supplement S1: Disaster Resuscitology , 1985 , pp. 176
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1985

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