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Anaphylactoid Reaction to Adenosine

Published online by Cambridge University Press:  28 June 2012

John G. Fata ,
Ronald N. Roth  and
Linda Carpenter
John G. Fata
Affiliation:
Clinical Instructor, Department of Medicine, Michigan State University, College of Human Medicine, Lansing, Michigan
Ronald N. Roth*
Affiliation:
Assistant Professor of Medicine, Division of Emergency Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania
Linda Carpenter
Affiliation:
Affiliated Residency in Emergency Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania
*
Division of Emergency Medicine, University of Pittsburgh, School of Medicine, 230 McKee Place, Suite 500, Pittsburgh, PA 15213USA
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Abstract

Adenosine (Adenocard) is an endogenous purine nucleoside that has been approved recently for intravenous treatment of paroxysmal supraventricular tachycardia. With a serum half-life of 10 seconds, reported side effects including facial flushing, dyspnea, and chest pressure are common, but very transient. An elderly woman who received adenosine for paroxysmal supraventricular tachycardia had a prolonged anaphylactoid reaction that required pharmacological treatment. This is the first reported case of prolonged anaphylactoid reaction to adenosine.

Keywords

adenosineanaphylactoid reactionsupraventricular tachycardiaurticaria
Type
Case Report
Information
Prehospital and Disaster Medicine , Volume 11 , Issue 2 , June 1996 , pp. 144 - 146
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1996

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