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X-Ray Powder Diffraction Data for Two Antihistamines: Clemizole Hydrochloride and Cyclizine Hydrochloride

Published online by Cambridge University Press:  10 January 2013

D.F. Rendle  and
E.J. Glazier
D.F. Rendle
Affiliation:
The Metropolitan Police Forensic Science Laboratory, 109, Lambeth Road, London SE1 7LP, U.K.
E.J. Glazier
Affiliation:
The Metropolitan Police Forensic Science Laboratory, 109, Lambeth Road, London SE1 7LP, U.K.
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Abstract

X-ray powder diffraction data for clemizole hydrochloride (1-p-chlorob-enzyl-2-pyrrolidin-1′-ylmethyl-benziminazole hydrochloride, C19H20ClN3.HCl) and cyclizine hydrochloride (1-benzhydryl-4-methylpiperazine hydrochloride, C18H22N2.HCl) are reported. Crystals of clemizole hydrochloride are monoclinic, space group P21/n with a = 29.940(5) Å, b = 10.963(2)Å, c = 5.515(2)Å, β = 90.98 (3)°, Z = 4 and Dx = 1.330g cm−3. Crystals of cyclizine hydrochloride are orthorhombic, space group Pna21 (or Pnam), with a = 11.816(1)Å, b = 13.609(2)Å, c = 9.999(1 )Å, Z = 4 and Dx = 1.251g cm−3.

Type
Research Article
Information
Powder Diffraction , Volume 6 , Issue 2 , June 1991 , pp. 104 - 106
Copyright
Copyright © Cambridge University Press 1991

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