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X-ray powder diffraction data for 7-ethyl-14-nitro-camptothecin, C22H19N3O6

Published online by Cambridge University Press:  07 September 2018

Wan Wang ,
Zili Suo ,
Lidong Liao  and
Hui Li
Wan Wang
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Zili Suo
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Lidong Liao
Affiliation:
Sichuan Sinovation Biotech Co., Ltd., Chengdu 610063, China
Hui Li*
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
a)Author to whom correspondence should be addressed. Electronic mail: [email protected]
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Abstract

X-ray powder diffraction (XRD) data, unit-cell parameters and space group for 7-ethyl-14-nitro-camptothecin, C22H19N3O6, are reported [a = 10.987(5) Å, b = 10.941 (9) Å, c = 8.438 (2) Å, α = 71.321(6)°, β = 96.145(0)°, γ = 95.139(3)°, unit-cell volume V = 953.87 Å3, Z = 2, ρcal = 1.467 g cm−3, and space group P-1]. All measured lines were indexed and are consistent with the P-1 space group. No detectable impurities were observed.

Keywords

X-ray powder diffraction7-ethyl-14-nitro-camptothecin
Type
New Diffraction Data
Information
Powder Diffraction , Volume 33 , Issue 4 , December 2018 , pp. 327 - 329
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Copyright
Copyright © International Centre for Diffraction Data 2018 

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References

Boultif, A. and Louër, D. (1991). “Indexing of powder diffraction patterns for low-symmetry lattices by the successive dichotomy method,” J. Appl. Crystallogr. 24, 987–993.Google Scholar
Cheng, X., Qiu, N., Yang, J., Liu, H., and Wen, J. (2015). “Preparation, characterization, and in vivo study of 7-ethyl-14-aminocamptothecin-loaded poly(ethylene glycol) 2000-poly(lactic acid)2000 polymeric micelles against H460 human nonsmall cell lung carcinoma,” J. Pharm. Sci.-US. 104(11): 3934–3942.Google Scholar
de Wolff, P. M. (1968). “A simplified criterion for the reliability of a powder pattern,” J. Appl. Crystallogr. 1, 108–113.Google Scholar
Duan, J., Cai, X., Meng, F., Sun, J. D., and Liu, Q. (2011). “14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment,” J. Med. Chem. 54(6): 1715–1723.Google Scholar
Pawley, G. S. (1981). “Unit-cell refinement from powder diffraction scans,” J. Appl. Crystallogr. 14(6), 357–361.Google Scholar
Smith, G. S. and Snyder, R. L. (1979). “FN: a criterion for rating powder diffraction patterns and evaluating the reliability of powder indexing,” J. Appl. Crystallogr. 12, 60–65.Google Scholar
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