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Powder X-ray diffraction of 1-(4-aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone, C15H19N3O2

Published online by Cambridge University Press:  29 October 2015

Qing Wang ,
Ya Ping Li ,
Shan Shan Li ,
Bin Tang  and
Hui Li
Qing Wang
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Ya Ping Li
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Shan Shan Li
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Bin Tang
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Hui Li*
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
a)Author to whom correspondence should be addressed. Electronic mail: [email protected].
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Abstract

X-ray powder diffraction data for 1-(4-aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone, C15H19N3O2, are reported [a = 14.877(4) Å, b = 5.893(6) Å, c = 18.984(3) Å, α = 90°, β = 122.298(3)°, γ = 90°, unit-cell volume V = 1406.86 Å3, Z = 4, and space group P21/c]. All measured lines were indexed and are consistent with the P21/c space group. No detectable impurities were observed.

Keywords

1-(4-aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinonepharmaceutical intermediateanticoagulantapixaban
Type
Rapid Communication
Information
Powder Diffraction , Volume 30 , Issue 4 , December 2015 , pp. 367
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Copyright
Copyright © International Centre for Diffraction Data 2015 

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References

Jiang, J. and Ji, Y. (2013). “Alternate synthesis of apixaban (BMS-562247), an inhibitor of blood coagulation factor Xa,” Synth. Commun. 43(1), 72–79.Google Scholar
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