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The Functional Sense of Mechanism

Published online by Cambridge University Press:  01 January 2022

Justin Garson
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Abstract

This article presents a distinct sense of ‘mechanism’, which I call the functional sense of mechanism. According to this sense, mechanisms serve functions, and this fact places substantive restrictions on the kinds of system activities ‘for which’ there can be a mechanism. On this view, there are no mechanisms for pathology; pathologies result from disrupting mechanisms for functions. Second, on this sense, natural selection is probably not a mechanism for evolution because it does not serve a function. After distinguishing this sense from similar explications of ‘mechanism’, I argue that it is ubiquitous in biology and has valuable epistemic benefits.

Type
Research Article
Information
Philosophy of Science , Volume 80 , Issue 3 , July 2013 , pp. 317 - 333
Copyright
Copyright © The Philosophy of Science Association

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Footnotes

†

I am grateful to Carl Craver, Lindley Darden, Blaine Ford, Joyce Havstad, Lenny Moss, Karen Neander, Stuart Newman, Anya Plutynski, and Eric Saidel, for comments and criticism of an earlier draft. I am also grateful to audience members at ISHPSSB 2011, PSA 2012, and a symposium at the University of Missouri–St. Louis, as well as participants of the D.C. History and Philosophy of Biology Reading Group, where some of this material was presented.

References

Amundson, Ron. 2000. “Against Normal Function.” Studies in History and Philosophy of Biological and Biomedical Sciences 31:33–53.CrossRefGoogle Scholar
Aydin, Birsen. 2011. “Effects of Thiacloprid, Deltamethrin and Their Combination on Oxidative Stress in Lymphoid Organs, Polymorphonuclear Leukocytes and Plasma of Rats.” Pesticide Biochemistry and Physiology 100:165–71.CrossRefGoogle Scholar
Bechtel, William, and Richardson, Robert C.. 1993. Discovering Complexity: Decomposition and Localization as Strategies in Scientific Research. Princeton, NJ: Princeton University Press.Google Scholar
Buss, David M. 2008. Evolutionary Psychology: The New Science of the Mind. 3rd ed. Boston: Pearson.Google Scholar
Buss, Leo W. 1987. The Evolution of Individuality. Princeton, NJ: Princeton University Press.Google Scholar
Casida, John E. 2009. “Pest Toxicology: The Primary Mechanisms of Pesticide Action.” Chemical Research in Toxicology 22:609–19.CrossRefGoogle ScholarPubMed
Craver, Carl F. 2001. “Role Functions, Mechanism, and Hierarchy.” Philosophy of Science 68:53–74.CrossRefGoogle Scholar
Craver, Carl F. 2013. “Functions and Mechanisms: A Perspectivalist View.” In Functions: Selection and Mechanisms, ed. Huneman, Philippe, 133–58. Dordrecht: Springer.Google Scholar
Cummins, Robert. 1975. “Functional Analysis.” Journal of Philosophy 72:741–65.CrossRefGoogle Scholar
Darden, Lindley. 2006. Reasoning in Biological Discoveries. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Davies, Paul S. 2001. Norms of Nature: Naturalism and the Nature of Functions. Cambridge, MA: MIT Press.CrossRefGoogle Scholar
Dretske, Fred. 1986. “Misrepresentation.” In Belief: Form, Content, and Function, ed. Bogdan, R., 17–36. Oxford: Clarendon.Google Scholar
Garson, Justin. 2008. “Function and Teleology.” In A Companion to the Philosophy of Biology, ed. Plutynski, Anya and Sarkar, Sahotra, 525–49. Malden, MA: Blackwell.Google Scholar
Sarkar, Sahotra 2011. “Selected Effects Functions and Causal Role Functions in the Brain: The Case for an Etiological Approach to Neuroscience.” Biology and Philosophy 26:547–65.Google Scholar
Sarkar, Sahotra 2012. “Function, Selection, and Construction in the Brain.” Synthese 189:451–81.Google Scholar
Glennan, Stuart. 1996. “Mechanisms and the Nature of Causation.” Erkenntnis 44:49–71.CrossRefGoogle Scholar
Glennan, Stuart 2002. “Contextual Unanimity and the Units of Selection Problem.” Philosophy of Science 69:118–37.CrossRefGoogle Scholar
Glennan, Stuart 2005. “Modeling Mechanisms.” Studies in History and Philosophy of Biological and Biomedical Sciences 36:443–64.CrossRefGoogle ScholarPubMed
Griffiths, Paul E. 2006. “Function, Homology, and Character Individuation.” Philosophy of Science 73:1–25.CrossRefGoogle Scholar
Hardcastle, Valerie G. 1999. “Understanding Functions.” In Where Biology Meets Psychology, ed. Hardcastle, Valerie G., 27–43. Cambridge, MA: MIT Press.CrossRefGoogle Scholar
Hardcastle, Valerie G. 2002. “On the Normativity of Functions.” In Functions: New Essays in the Philosophy of Psychology and Biology, ed. Ariew, Andre, Cummins, Robert, and Perlman, Mark, 144–56. Oxford: Oxford University Press.Google Scholar
Kauer, Julie A., and Malenka, Robert C.. 2007. “Synaptic Plasticity and Addiction.” Nature Reviews Neuroscience 8:844–58.CrossRefGoogle ScholarPubMed
Kauffman, Stuart A. 1970. “Articulation of Parts Explanation in Biology and the Rational Search for Them.” Boston Studies in the Philosophy of Science 8:257–72.Google Scholar
Kitcher, Philip. 1993. “Function and Design.” Midwest Studies in Philosophy 18:379–97.CrossRefGoogle Scholar
Landsberg, Jennifer, et al. 2012. “Melanomas Resist T-Cell Therapy through Inflammation-Induced Reversible Dedifferentiation.” Nature 490:412–16.CrossRefGoogle ScholarPubMed
Long, Michael S. 2010. “A Possible Physical Mechanism of Cancer Metastasis.” Blog post, National Association of Science Writers. http://www.nasw.org/users/mslong/2010/2010_01/Metastasis.htm.Google Scholar
Lynch, Conor C., et al. 2005. “MMP-7 Promotes Prostate Cancer-Induced Osteolysis via the Solubilization of RANKL.” Cancer Cell 7:485–96.CrossRefGoogle ScholarPubMed
Machamer, Peter, Darden, Lindley, and Craver, Carl F.. 2000. “Thinking about Mechanisms.” Philosophy of Science 67:1–25.CrossRefGoogle Scholar
Marino, Melissa. 2005. “Team Identifies Mechanism of Cancer-Induced Bone Destruction.” Reporter, Vanderbilt University Medical Center. http://www.mc.vanderbilt.edu/reporter/index.html?ID=3979.Google Scholar
Millikan, Ruth G. 1989. “In Defense of Proper Functions.” Philosophy of Science 56:288–302.CrossRefGoogle Scholar
Moghaddam-Taaheri, Sara. 2011. “Understanding Pathology in the Context of Physiological Mechanisms: The Practicality of a Broken-Normal View.” Biology and Philosophy 26:603–11.CrossRefGoogle Scholar
Moss, Lenny. 2012. “Is the Philosophy of Mechanism Philosophy Enough?” Studies in History and Philosophy of Science C 43:164–72.Google Scholar
Neander, Karen. 1991. “Functions as Selected Effects: The Conceptual Analysts’ Defense.” Philosophy of Science 58:168–84.CrossRefGoogle Scholar
Neander, Karen 2008. “Teleological Theories of Mental Content.” In The Oxford Handbook of Philosophy of Biology, ed. Ruse, M., 381–409. Oxford: Oxford University Press.Google Scholar
Ruse, M. Forthcoming. Intentionality. Cambridge, MA: MIT Press.Google Scholar
Piccinini, Gualtiero. 2010. “The Mind as Neural Software? Understanding Functionalism, Computationalism, and Functional Computationalism.” Philosophy and Phenomenological Research 81:269–311.CrossRefGoogle Scholar
Piccinini, Gualtiero, and Craver, Carl F.. 2011. “Integrating Psychology and Neuroscience: Functional Analyses as Mechanism Sketches.” Synthese 183:283–311.CrossRefGoogle Scholar
Rolli, Claudio G., et al. 2010. “Impact of Tumor Cell Cytoskeleton Organization on Invasiveness and Migration: A Microchannel-Based Approach.” PLoS One 5:e8726.CrossRefGoogle ScholarPubMed
Rosenberg, Alex, and Neander, Karen. 2009. “Are Homologies (Selected Effect or Causal Role) Function Free?” Philosophy of Science 76:307–34.CrossRefGoogle Scholar
Rowan, M. J., Klyubin, I., Cullen, W. K., and Anwyl, R.. 2003. “Synaptic Plasticity in Animal Models of Early Alzheimer’s Disease.” Philosophical Transactions of the Royal Society of London B 358:821–28.Google ScholarPubMed
Thagard, Paul. 1999. How Scientists Explain Disease. Princeton, NJ: Princeton University Press.CrossRefGoogle Scholar
Tooby, John, and Cosmides, Leda. 2006. “Toward Mapping the Evolved Functional Organization of Mind and Brain.” In Conceptual Issues in Evolutionary Biology, 3rd ed., ed. Sober, Elliott, 175–95. Cambridge, MA: MIT Press.Google Scholar
Williams, George C. 1966. Adaptation and Natural Selection. Princeton, NJ: Princeton University Press.Google Scholar
Wimsatt, William C. 1972. “Complexity and Organization.” In PSA 1972: Proceedings of the 1972 Biennial Meeting of the Philosophy of Science Association, ed. Schaffner, Kenneth F. and Cohen, Robert S., 67–86. East Lansing, MI: Philosophy of Science Association.Google Scholar