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Investigation of the validity and reliability of the Turkish version of the Functional Assessment of Cancer Therapy—Cognitive Function in cancer patients

Published online by Cambridge University Press:  02 September 2021

Songül Atasavun Uysal Open the ORCID record for Songül Atasavun Uysal [Opens in a new window] ,
Vesile Yildiz Kabak Open the ORCID record for Vesile Yildiz Kabak [Opens in a new window] ,
Yusuf Karakas Open the ORCID record for Yusuf Karakas [Opens in a new window] ,
Erdem Karabulut Open the ORCID record for Erdem Karabulut [Opens in a new window] ,
Deniz Erdan Kocamaz Open the ORCID record for Deniz Erdan Kocamaz [Opens in a new window] ,
İlke Keser Open the ORCID record for İlke Keser [Opens in a new window] ,
Kadirhan Özdemir Open the ORCID record for Kadirhan Özdemir [Opens in a new window]  and
Tülin Düger Open the ORCID record for Tülin Düger [Opens in a new window]
Songül Atasavun Uysal*
Affiliation:
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey
Vesile Yildiz Kabak
Affiliation:
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey
Yusuf Karakas
Affiliation:
Medical Oncology Clinic, Acibadem Bodrum Hospital, Mugla, Turkey
Erdem Karabulut
Affiliation:
Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Deniz Erdan Kocamaz
Affiliation:
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Hasan Kalyoncu University, Gaziantep, Turkey
İlke Keser
Affiliation:
Department of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey
Kadirhan Özdemir
Affiliation:
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bakircay University, Izmir, Turkey
Tülin Düger
Affiliation:
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey
*
Author for correspondence: Songül Atasavun Uysal, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey. E-mail: [email protected]
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Abstract

Objective

The Functional Assessment of Cancer Therapy—Cognitive Function (FACT-Cog) is a questionnaire that is used to evaluate the quality of life and cognitive functions according to individual self-reports. The aim of this study was to investigate the validity and reliability of the Turkish version of the FACT-Cog.

Methods

Cancer patients who were treated with chemo or radiotherapy and had a score of 24/30 and more in Mini-Mental State Examination (MMSE) were included in this study. Cognitive functions assessed with the FACT-Cog and the European Organization of Research and Treatment of Cancer Quality of Life Core Questionnaire Core 30: Cognitive Function subscale (EORTC QLQ-CF).

Results

One hundred and forty cancer patients [female = 87 (62.1%), male = 53 (37.9%)] were included. The mean age of the participants was 47.93 ± 11.90 years. The Cronbach's α of the FACT-Cog scale was 0.82. Test–retest intraclass correlation coefficient values of the FACT-Cog questionnaire were varied from 0.855 to 0.954. There were found low correlations between the total score of the FACT-Cog and the MMSE (r = 0.26, p = 0.002), and moderate correlations between the EORTC QLQ-CF subscale and the FACT-Cog (r = −0.43; p < 0.001).

Significance of results

It showed the validity and reliability of the Turkish version of the FACT-Cog questionnaire for cancer patients. It may be beneficial to use this questionnaire for the effects of cancer treatment.

Keywords

Cancer treatmentCognitive functionFunctional assessmentQuality of life
Type
Original Article
Information
Palliative & Supportive Care , Volume 20 , Issue 5 , October 2022 , pp. 694 - 700
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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References

Aaronson, NK, Ahmedzai, S, Bergman, B, et al. (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute 85, 365–376. doi:10.1093/jnci/85.5.365CrossRefGoogle ScholarPubMed
Arevalo-Rodriguez, I, Roqué, I, Figuls, M, et al. (2015) Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI). Cochrane Database of Systematic Reviews CD010783. doi:10.1002/14651858.CD010783.pub2Google Scholar
Bonomi, AE, Cella, DF, Hahn, EA, et al. (1996) Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 5, 309–320. doi:10.1007/BF00433915CrossRefGoogle ScholarPubMed
Bray, F, Ferlay, J, Soerjomataram, I, et al. (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians 68, 394–424. doi:10.3322/caac.21492Google ScholarPubMed
Chen, ML, Miaskowski, C, Liu, LN, et al. (2012) Changes in perceived attentional function in women following breast cancer surgery. Breast Cancer Research and Treatment 131, 599–606. doi:10.1007/s10549-011-1760-3CrossRefGoogle ScholarPubMed
Cheung, YT and Chan, A (2013) Linguistic validation of Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog): Methodological concerns. Supportive Care in Cancer 21, 655–656. doi:10.1007/s00520-012-1631-4CrossRefGoogle ScholarPubMed
Cheung, YT, Shwe, M, Chui, WK, et al. (2012) Effects of chemotherapy and psychosocial distress on perceived cognitive disturbances in asian breast cancer patients. Annals of Pharmacotherapy 46, 1645–1655. doi:10.1345/aph.1R408CrossRefGoogle ScholarPubMed
Conroy, SK, McDonald, BC, Smith, DJ, et al. (2013) Alterations in brain structure and function in breast cancer survivors: Effect of post-chemotherapy interval and relation to oxidative DNA damage. Breast Cancer Researcd and Treatment 137, 493–502. doi:10.1007/s10549-012-2385-xCrossRefGoogle ScholarPubMed
Creavin, ST, Wisniewski, S, Noel Storr, AH, et al. (2016) Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. Cochrane Database Systematic Reviews CD011145. doi:10.1002/14651858.CD011145.pub2Google ScholarPubMed
Demirci, S, Eser, E, Ozsaran, Z, et al. (2011) Validation of the Turkish versions of EORTC QLQ-C30 and BR23 modules in breast cancer patients. Asian Pacific Journal of Cancer Prevention 12, 1283–1287.Google ScholarPubMed
George, D (2010) SPSS for Windows Step by Step: A Simple Guide and Reference, 17.0 Update, 10th ed. Boston: Pearson.Google Scholar
Guzelant, A, Goksel, T, Ozkok, S, et al. (2004) The European Organization for Research and Treatment of Cancer QLQ-C30: An examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. European Journal of Cancer Care 13, 135–144. doi:10.1111/j.1365-2354.2003.00435.xCrossRefGoogle ScholarPubMed
Henneghan, A (2016) Modifiable factors and cognitive dysfunction in breast cancer survivors: A mixed-method systematic review. Supportive Care in Cancer 24, 481–497. doi:10.1007/s00520-015-2927-yCrossRefGoogle ScholarPubMed
Joly, F, Lange, M, Rigal, O, et al. (2012) French version of the Functional Assessment of Cancer Therapy-Cognitive function (FACT-Cog) version 3. Supportive Care in Cancer 20, 3297–3305. doi:10.1007/s00520-012-1439-2CrossRefGoogle ScholarPubMed
Lent, L, Hahn, E, Eremenco, S, et al. (1999) Using cross-cultural input to adapt the Functional Assessment of Chronic Illness Therapy (FACIT) scales. Acta Oncology 38, 695–702. doi:10.1080/028418699432842Google ScholarPubMed
McDonald, BC, Conroy, SK, Ahles, TA, et al. (2012) Alterations in brain activation during working memory processing associated with breast cancer and treatment: A prospective functional magnetic resonance imaging study. Journal of Clinical Oncology 30, 2500–2508. doi:10.1200/JCO.2011.38.5674CrossRefGoogle ScholarPubMed
McHorney, CA (1995) Individual-patient monitoring in clinical practice: Are available health status surveys adequate? Quality of Life Research 293–307. doi:10.1007/BF01593882CrossRefGoogle ScholarPubMed
Olson, K, Hewit, J, Slater, LG, et al. (2016) Assessing cognitive function in adults during or following chemotherapy: A scoping review. Supportive Care in Cancer 24, 3223–3234. doi:10.1007/s00520-016-3215-1Google ScholarPubMed
Park, JH, Bae, SH, Jung, YS, et al. (2015) The psychometric properties of the Korean version of the Functional Assessment of Cancer Therapy-Cognitive (FACT-Cog) in Korean patients with breast cancer. Supportive Care in Cancer 23, 2695–2703. doi:10.1007/s00520-015-2632-xCrossRefGoogle ScholarPubMed
Pullens, MJ, De Vries, J and Roukema, JA (2010) Subjective cognitive dysfunction in breast cancer patients: A systematic review. Psycho-oncology 19, 1127–1138. doi:10.1002/pon.1673CrossRefGoogle ScholarPubMed
Redeker, NS, Lev, EL and Ruggiero, J (2000) Insomnia, fatigue, anxiety, depression, and quality of life of cancer patients undergoing chemotherapy. Scholarly Inquiry for Nursing Practice 14, 275–290.Google ScholarPubMed
Schreiber, JB, Stage, FK, Barlow, EA, et al. (2010) Reporting structural equation modeling and confirmatory factor analysis results: A review. Journal of Educational Research 323–338. doi:10.3200/JOER.99.6.323-338Google Scholar
Stein, KD, Syrjala, KL and Andrykowsk, MA (2008) Physical and psychological long-term and late effects of cancer. Cancer 112, 2577–2592. doi:10.1002/cncr.23448CrossRefGoogle ScholarPubMed
Tchen, N, Juffs, HG, Downie, FP, et al. (2003) Cognitive function, fatigue, and menopausal symptoms in women receiving adjuvant chemotherapy for breast cancer. Journal of Clinical Oncology 21, 4175–4183. doi:10.1200/JCO.2003.01.119CrossRefGoogle ScholarPubMed
Vardy, J, Wong, K, Yi, QL, et al. (2006) Assessing cognitive function in cancer patients. Supportive Care in Cancer 14, 1111–1118. doi:10.1007/s00520-006-0037-6CrossRefGoogle ScholarPubMed
Vardy, J, Rourke, S and Tannock, IF (2007) Evaluation of cognitive function associated with chemotherapy: A review of published studies and recommendations for future research. Journal of Clinical Oncology 25, 2455–2463. doi:10.1200/JCO.2006.08.1604CrossRefGoogle ScholarPubMed
Wagner, LI, Butt, Z, Lai, J, et al. (2009) Measuring patient self-reported cognitive function: Development of the Functional Assessment of Cancer Therapy–Cognitive Function Instrument. Journal of Supportive Oncology 7, 32–39.Google Scholar
Wild, D, Grove, A, Martin, M, et al. (2005) Principles of good practice for the translation and cultural adaptation process for patient-reported outcomes (PRO) measures: Report of the ISPOR task force for translation and cultural adaptation. Value in Health 8, 94–104. doi:10.1111/j.1524-4733.2005.04054.xCrossRefGoogle ScholarPubMed