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Is spiritual well-being related to survival time of inpatients with advanced cancer? An East Asian cohort study

Published online by Cambridge University Press:  27 June 2022

Yusuke Hiratsuka Open the ORCID record for Yusuke Hiratsuka [Opens in a new window] ,
Sang-Yeon Suh Open the ORCID record for Sang-Yeon Suh [Opens in a new window] ,
Seon Hye Won ,
Sung Eun Choi ,
Sun-Hyun Kim ,
Shao-Yi Cheng ,
Ping-Jen Chen ,
Seok-Joon Yoon ,
Su-Jin Koh  and
Shin Ae Park
...Show all authors
Yusuke Hiratsuka
Affiliation:
Department of Palliative Medicine, Tohoku University School of Medicine, Sendai, Japan Department of Palliative Medicine, Takeda General Hospital, Aizuwakamatsu, Japan
Sang-Yeon Suh*
Affiliation:
Hospice & Palliative Care Center, Department of Family Medicine, Dongguk University Ilsan Hospital, Goyang-si, South Korea Department of Medicine, Dongguk University Medical School, Seoul, South Korea
Seon Hye Won
Affiliation:
Hospice & Palliative Care Center, Department of Family Medicine, Dongguk University Ilsan Hospital, Goyang-si, South Korea
Sung Eun Choi
Affiliation:
Department of Statistics, Dongguk University, Seoul, South Korea
Sun-Hyun Kim
Affiliation:
Department of Family Medicine, School of Medicine, Catholic Kwandong University International St. Mary's Hospital, Incheon, South Korea
Shao-Yi Cheng
Affiliation:
Department of Family Medicine, College of Medicine and Hospital, National Taiwan University, Taipei, Taiwan
Ping-Jen Chen
Affiliation:
Department of Family Medicine, Kaohsiung Medical University Hospital, and School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Marie Curie Palliative Care Research Department, Division of Psychiatry, University College London, London, UK
Seok-Joon Yoon
Affiliation:
Department of Family Medicine, Chungnam National University Hospital, Daejeon, South Korea
Su-Jin Koh
Affiliation:
Department of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, South Korea
Shin Ae Park
Affiliation:
Hospice & Palliative Care Center, Department of Family Medicine, Seobuk Hospital, Seoul Metropolitan Government, Seoul, South Korea
Ji-Yeon Seo
Affiliation:
Hospice & Palliative Care Center, Department of Family Medicine, Seobuk Hospital, Seoul Metropolitan Government, Seoul, South Korea
David Hui
Affiliation:
Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Takashi Yamaguchi
Affiliation:
Department of Palliative Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
Tatsuya Morita
Affiliation:
Division of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Hamamatsu, Japan
Satoru Tsuneto
Affiliation:
Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Masanori Mori
Affiliation:
Division of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Hamamatsu, Japan
Akira Inoue
Affiliation:
Department of Palliative Medicine, Tohoku University School of Medicine, Sendai, Japan
*
Author for correspondence: Sang-Yeon Suh, Department of Medicine, Dongguk University Medical School, Pildong 1–30, Jung-gu, Seoul, South Korea. E-mail: [email protected]
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Abstract

Objectives

It has been suggested that psychosocial factors are related to survival time of inpatients with cancer. However, there are not many studies examining the relationship between spiritual well-being (SWB) and survival time among countries. This study investigated the relationship between SWB and survival time among three East Asian countries.

Methods

This international multicenter cohort study is a secondary analysis involving newly admitted inpatients with advanced cancer in palliative care units in Japan, South Korea, and Taiwan. SWB was measured using the Integrated Palliative Outcome Scale (IPOS) at admission. We performed multivariate analysis using the Cox proportional hazards model to identify independent prognostic factors.

Results

A total of 2,638 patients treated at 37 palliative care units from January 2017 to September 2018 were analyzed. The median survival time was 18.0 days (95% confidence interval [CI] 16.5–19.5) in Japan, 23.0 days (95% CI 19.9–26.1) in Korea, and 15.0 days (95% CI 13.0–17.0) in Taiwan. SWB was a significant factor correlated with survival in Taiwan (hazard ratio [HR] 1.27; 95% CI 1.01–1.59; p = 0.04), while it was insignificant in Japan (HR 1.10; 95% CI 1.00–1.22; p = 0.06), and Korea (HR 1.02; 95% CI 0.77–1.35; p = 0.89).

Significance of results

SWB on admission was associated with survival in patients with advanced cancer in Taiwan but not Japan or Korea. The findings suggest the possibility of a positive relationship between spiritual care and survival time in patients with far advanced cancer.

Keywords

Advanced cancerEnd of lifePalliative careSpiritual well-beingSurvival time
Type
Original Article
Information
Palliative & Supportive Care , Volume 21 , Issue 3 , June 2023 , pp. 483 - 491
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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