Guido di Pietro, known to posterity as Fra Angelico, was born of peasant stock in Mugello, probably around 1400. He and his brother trained as illuminators and miniaturists and, when Angelico was about 21, they joined the Observant Dominican community of San Domenico in Fiesole above Florence. Professed as Brother John, Angelico’s ‘pastoral work’ while studying for the priesthood was to paint for San Domenico, Sta Maria Novella, and elsewhere. These early commissions made him famous and funded his workshop. If he was still learning priestcraft he was also still learning to paint: for his skills as an illuminator were little preparation for altarpiece design, a duty laid on his shoulders along with his Dominican scapular. So he became acquainted with the works of his contemporaries such as Masaccio, Masolino, Gentile and Sassetta.

His most important contact, however, was Cosimo De Medici, a patron not only of the arts but of the religious orders, especially the more radical mendicants. On return to power in 1434, he set about installing the Observant Dominicans in Florence, renovating an abandoned monastery for them which was to represent “the best in Christian humanism”.