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Towards Next-Generation Proteomic Assays: Functional Materials as Sieving Matrices and Binding Scaffolds

Published online by Cambridge University Press:  29 December 2011

Samuel Q. Tia ,
Alex J. Hughes ,
Kelly Karns ,
M. Kursad Araz ,
Mei He ,
Dohyun Kim  and
Amy E. Herr
Samuel Q. Tia
Affiliation:
University of California, Berkeley, Bioengineering, 308B Stanley Hall MC # 1762, Berkeley, CA 94720, U.S.A.
Alex J. Hughes
Affiliation:
University of California, Berkeley, Bioengineering, 308B Stanley Hall MC # 1762, Berkeley, CA 94720, U.S.A.
Kelly Karns
Affiliation:
University of California, Berkeley, Bioengineering, 308B Stanley Hall MC # 1762, Berkeley, CA 94720, U.S.A.
M. Kursad Araz
Affiliation:
University of California, Berkeley/University of California San Francisco, Graduate Program in Bioengineering, Berkeley, CA 94720, U.S.A.
Mei He
Affiliation:
University of California, Berkeley/University of California San Francisco, Graduate Program in Bioengineering, Berkeley, CA 94720, U.S.A.
Dohyun Kim
Affiliation:
University of California, Berkeley/University of California San Francisco, Graduate Program in Bioengineering, Berkeley, CA 94720, U.S.A.
Amy E. Herr
Affiliation:
University of California, Berkeley, Bioengineering, 308B Stanley Hall MC # 1762, Berkeley, CA 94720, U.S.A. University of California, Berkeley/University of California San Francisco, Graduate Program in Bioengineering, Berkeley, CA 94720, U.S.A.
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Abstract

Next-generation bioanalytical approaches for protein-level measurements are advanced by the integration capacity of microfluidic design strategies, as well as the fine fluid and material control possible. Photopatterning of polymers within fluidic volumes is a key tool in the suite of technologies available for seamless integration of assay measurement modalities, as well as rapid target detection. Here, we overview recent advances in heterogeneous and homogeneous immunoassays using functional polymers, electrophoretic transport, and microdevices.

Keywords

polymerdevicesfluidics
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1415: Symposium HH/II/TT – MEMS, BioMEMS and Bioelectronics– Materials and Devices , 2012 , mrsf11-1415-ii06-05
Copyright
Copyright © Materials Research Society 2011

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References

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