Hostname: page-component-6bf8c574d5-8gtf8 Total loading time: 0 Render date: 2025-02-18T06:43:35.011Z Has data issue: false hasContentIssue false
  • English
  • Français

Tissue Tolerance and Antibacterial Effectiveness of Hydroxylapatite Silver Phosphate Ceramics

Published online by Cambridge University Press:  26 February 2011

J. Eitenmülleri ,
K. Hangst ,
G. Peters  and
W. Golsong
J. Eitenmülleri
Affiliation:
Chirurgische Universitätsklinik “Bergmannsheil”, Gilsingstr.14 4630 Bochum 1, F.R.Germany
K. Hangst
Affiliation:
Museum für ostasiatische Kunst, Universitätsstr. 100, 5 Koln 41
G. Peters
Affiliation:
Hygieneinstitut der Universität Köln, Goldenfelsstr., 5 Kö1n 41
W. Golsong
Affiliation:
Chirurgische Abteilung des Mareinkrankenhauses Oberhausen
Get access

Abstract

The tissue compatibility of the hydroxylapatite silver phosphate ceramics could be demonstrated in the cortex of mongrel dogs. The assessment was done by histomorphometrical methods. The toxicity depends on the content of silver phosphate and the method of manufacture.- In treatment of an experimentally induced osteomyelitis in dogs, hydroxylapatite silver phosphate containing granules had better success than an autologous spongiosa graft or hydroxylapatite granules without the agent.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 277
Copyright
Copyright © Materials Research Society 1988

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Brandyk, D.F., Berni, G.A., Theile, B.L., Towne, J.B.: Aortofemoral Graft Injection Due to Staphylococcus Epidermidis. Arch.Surg., 119: 102–108, 1984 Google Scholar
2. Dougherty, S.H., Simmons, R.L.: Infections in Bionic Man: The Pathobiology of Infections in Prosthetic Devices-Part I. Curr. Prob.Surg. 19: 221–264, 1982 Google Scholar
3. Holt, R.J.: Bacteriological Studies Colonised Ventriculoatrial Shunts. Devel.Med. and Child.Neurol.,12 (Supplement 22): 83–87, 1970 Google Scholar
4. Marrie, T.J., Nelligan, Joyce, Costerton: A Scanning and Transmission Electron Microscopic Studie of an Infected Endocardial Pacemaker Lead. Circulation, 66: 1339–1341, 1982 Google Scholar
5. Bombelli, R., Giangrande, A., Mallacrida, V., Puricelli, G.: The Controll of Infection in Orthopedic Surgery. Orthop.Rev.,10: 67–72, Feb.1981 Google Scholar
6. Buchholz, H.W., Elson, R.A., Engelbrecht, E., Lodenkämper, H., Rottger, J., Siegel, A.: Management of Deep Infection of Total Hip Replacement. J.Bone and Joint Surg., 63–B(3): 342–353, 1981 Google Scholar
7. Costerton, J.W., Irvin, R.T., Cheng, K.-J.: The Bacterial Glycocalyx in Nature and Disease. Ann.Rev.Microbiol.,35: 299–324,1981 Google Scholar
8. D'Ambrosia, R.D., Sohji, H., Heater, R.: Secondarily Infected Total Joint Replacements by Hematogenous Spread. J.Bone and Joint Surg. 58–A: 450–453, June 1976 Google Scholar
9. Gristina, A.G., Costerton, J.W.: Bacterial Adherence and the Glycocalyx and Their Role in Musculosceletal Infection. Orthop. Clin.North America, 15: 517–535, 1984 Google Scholar
10. Gristina, A.G., Chosterton, J.W.: Bacteria-Laden Biofilms: A Hazard to Orthopedic Prothesis. Infect.Surg.,3: 655–662, 1984 Google Scholar
11. Gristina, A.G., Kolkin, J.: Current Concepts Review.Total Joint Replacement and Sepsis. J.Bone and Joint Surg.,65–A: 128–134,1983 Google Scholar
12. Gristina, A.G., Costerton, J.W., Leake, E., Kolkin, J., Wright, M.J.: Bacteria and Their Relationship to Biomaterials. Orthop. Trans., 5: 332, 1981 Google Scholar
13. Katz, S., Izhar, M., Mirelman, D.: Bacterial Adherence to Surgical Suture. A Possible Factor in Suture Inducted Infection. Ann.Surg. 194: 35–41, 1981 Google Scholar
14. Eitenmüller, J.: Die Bedeutung der synthetischen Kalzium-Phosphatkeramiken als Knochenersatzmaterial. Orthopäde, Springer Verlag, 15: 30–35 , 1986 Google Scholar
15. de Groot, K.: Bioceramics of Calcium Phosphate. CRC Press, Boca Raton, 146 pp., 1983 Google Scholar
16. Osborn, J.F.: Implantatwerkstoff Hydroxylapatidkeramik. Grundlagen und klinische Anwendung. Quintessenz Bibliothek, Berlin, Chicago,London,Rio de Janeiro und Tokio, 1985 Google Scholar
17. Hangst, K., Eitenmüller, J., Weltin, R., Peters, G.: Hydoxylapatite Silver Phosphate Ceramics, Its Production, Analysis and Biological Testing of its Antibacterial Efectiveness. Materials Research Society. Biomedical Materials, in press.Google Scholar
18. Gristina, A.G., Costerton, J.W.: Bacterial Adherence to Biomaterials and Tissue. J.Bone and Joint Surg., 67–A: 264–273,1985 Google Scholar
19. Christensen, G.D., Simpson, W.A., Bisno, A.L., Beachney, E.H.: Adherence of Slime-Producing Strains of Staphylococcus epidermides to smooth surfaces. Infect. and Immun., 37: 318–326, 1982 Google Scholar
20. Gristina, A.G., Rovere, G.D.: An in vitro Study of the Effects of Metals Used in Internal Fixation on Bacterial Growth and Dissamination. In Proceedings of the Orthopedic Research Society.J. Bone and Joint Surg. 45–A: 1104, 1963 Google Scholar
21. Locci, R., Peters, G., Pulverer, G.: Microbial Colonization of Prothetic Devices. I.Microtopographical Characteristics of Intravenous Catheters as Detected by Scanning Electron Microscopy. Zentralbl.Bakter.Mikrobiol.Hyg.,B.,173: 285–292, 1981 Google Scholar
22. Peters, G., Locci, R., Pulverer, G.: Microbial Colonization of Prothetic Device.II. SCanning Electron Microscopy of Naturally Infected Intravenous Chatheters. Zentralbl.Mikrobiol.Bakter.Hyg. B., 173: 293–299, 1981 Google Scholar
23. Krause, K.: Versuche zur Konservierung von Augenarzneinen durch oligodynamisch wirksame Silbermengen. Dissertationen. Philipps-Universität Marburg an der Lahn, 1978 Google Scholar