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Tetherless, 3D, Micro-Nanoscale Tools and Devices for Lab on a Chip Applications

Published online by Cambridge University Press:  31 January 2011

David H Gracias
David H Gracias*
Affiliation:
[email protected], Johns Hopkins University, Chemical and Biomolecular Engineering, 3400 N Charles Street, 125 Maryland Hall, Baltimore, Maryland, 21218, United States, 410-516-5284, 410-516-5510
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Abstract

On the macroscale, a laboratory scientist uses a large number of tools such as flasks, crucibles, spatulas, filter funnels, test tube holders and grippers. If laboratory procedures are to be miniaturized within chips, micro and nanoscale analogs of these macroscopic tools could provide enhanced functionality. In this paper, I describe research efforts in our group aimed at engineering three dimensional, tetherless and lithographically patterned miniaturized structures for lab on a chip applications.

Keywords

microelectro-mechanical (MEMS)self-assemblyfluidics
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1191: Symposium OO – Materials and Strategies for Lab-on-a-Chip–Biological Analysis, Cell-Material Interfaces and Fluidic Assembly of Nanostructures , 2009 , 1191-OO02-02
Copyright
Copyright © Materials Research Society 2009

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References

1 Teh, S.Y., Lin, R. Hung, L.H. , Lung-Hsin and Lee, A. P. Lab Chip, 8, 198 (2008)10.1039/b715524gGoogle Scholar
2 Gijs, A. M. Microfluidics and Nanofluidics 1, 22 (2004)Google Scholar
3 Leong, T. G. Randall, C. L. Benson, B. R. Zarafshar, A.M. and Gracias, D. H. Lab Chip 8, 1621 (2008)10.1039/b809098jGoogle Scholar
4 Leong, T. Lester, P. Koh, T. Call, E. and Gracias, D. H. Langmuir 23, 8747 (2007)10.1021/la700913mGoogle Scholar
5 Leong, T. G. Benson, B. R. Call, E. K. and Gracias, D. H. Small 4, 1605 (2008)10.1002/smll.200800280Google Scholar
6 Randall, C. L. Gillespie, A. Singh, S. Leong, T. G. and Gracias, D. H. Anal. Bioanal. Chem. 393, 1217–1224 (2009)10.1007/s00216-008-2538-2Google Scholar
7 Gimi, B. Leong, T. Gu, Z. Yang, M., Artemov, D. Bhujwalla, Z. M. and Gracias, D. H. Biomed. Microdevices 7, 341 (2005)10.1007/s10544-005-6076-9Google Scholar
8 Ye, H. Randall, C. Leong, T. Slanac, D. Call, E. and Gracias, D. H. Angew. Chem., Int. Ed. 46, 4991 (2007)10.1002/anie.200604414Google Scholar
9 Leong, T. G. Randall, C. L. Benson, B. R. Bassik, N. Stern, G. M. and Gracias, D. H. Proc. Natl. Acad. Sci. U. S. A. 106, 703 (2009)10.1073/pnas.0807698106Google Scholar
10 Randhawa, J. S. Leong, T. G. Bassik, N. Benson, B. R. Jochmans, M. T. and Gracias, D.H. J. Am. Chem. Soc. 130, 7238 (2008)10.1021/ja806961pGoogle Scholar
11 Cho, J. H. Hu, S. and Gracias, D. H. App. Phys. Lett. 93, 043505/1 (2008).Google Scholar