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Tailoring nanopores for efficient sensing of different biomolecules

Published online by Cambridge University Press:  01 February 2011

Oukhaled AbdelGhani ,
Laurent Bacri ,
Eric Bourhis ,
Birgetta schiedt ,
Ali Madouri ,
Gilles Patriarche ,
R Jede ,
J.M. Guegan ,
Philippe Guegan  and
Loic Auvray
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Oukhaled AbdelGhani
Affiliation:
[email protected]@gmail.fr
Laurent Bacri
Affiliation:
[email protected]
Eric Bourhis
Affiliation:
[email protected]
Birgetta schiedt
Affiliation:
[email protected]
Ali Madouri
Affiliation:
[email protected]
Gilles Patriarche
Affiliation:
[email protected]
Philippe Guegan
Affiliation:
[email protected]
Loic Auvray
Affiliation:
[email protected]
Juan Pelta
Affiliation:
[email protected]
Jacques Gierak
Affiliation:
[email protected]
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Abstract

Highly Focused Ion Beams (FIB) are used to produce in one step large quantities of solid state nanopores drilled in thin dielectric films with high reproducibility and well controlled morphologies. We explore both the production of nanopores of various diameters and study their applicability to different biological molecules such as DNA, or folded and unfolded proteins, and then we compare their transport properties. We also report on the translocation of Fibronectin which an original experiment made possible is using the methodology described in this article.

Keywords

ion-beam processingpolymerbiological
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1253: Symposium K – Functional Materials and Nanostructures for Chemical and Bochemical Sensing , 2010 , 1253-K10-33
Copyright
Copyright © Materials Research Society 2010

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