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Synthetic Helical Polymers and Diblock Copolymers: Building Blocks for Biocompatible/Biofunctional Helical Superstructures

Published online by Cambridge University Press:  30 July 2012

Biswajit Sannigrahi ,
Juana Mendenhall  and
Ishrat M Khan
Biswajit Sannigrahi
Affiliation:
Department of Chemistry and Center for Functional Nanoscale Materials, Clark Atlanta University, Atlanta, GA 30314, U.S.A.
Juana Mendenhall
Affiliation:
Department of Chemistry and Center for Functional Nanoscale Materials, Clark Atlanta University, Atlanta, GA 30314, U.S.A. Current Address: Department of Chemistry, Morehouse College, Atlanta, GA 30314, U.S.A.
Ishrat M Khan
Affiliation:
Department of Chemistry and Center for Functional Nanoscale Materials, Clark Atlanta University, Atlanta, GA 30314, U.S.A.
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Abstract

Bottom-up design of materials via self-assembly with appropriate building blocks offers the possibility of developing innovative three-dimensional all synthetic materials with new functionalities. Helical optically active poly(3-methyl-4-vinylpyridine)/(R) and (S) mandelic acid and helical optically active poly(3-methyl-4-vinylpyridine) (P3M4VP)/ D- and L- amino acid complexes have been prepared. A diblock copolymer of helical poly[(3-methyl-4-vinylprydine)/mandelic acid complex]-block-poly(styrene) has been processed into smectic layer-like helical-bundle structures on silicon wafer. Additionally, optically active helical poly(2-methoxystyrene) (P2PMS) has been synthesized and the surfaces of the chiral helical P2MS have been shown to be effective as supports for mouse and human osteoblast cells. The cell attachment and growth data demonstrate that the chiral P2MS surfaces were better supports compared to achiral P2MS surfaces.

Keywords

polymerself-assemblybiomimetic (assembly)
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1450: Symposium CC – Hierarchically Self-Assembled Materials—From Molecule to Nano and Beyond , 2012 , mrss12-1450-cc06-27
Copyright
Copyright © Materials Research Society 2012

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References

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