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Synthesis and characterization of magnetite nanoparticles modified with PEG-based amphiphilic copolymers

Published online by Cambridge University Press:  12 April 2012

Ryo Kasuya ,
Teppei Kikuchi ,
Jeyadevan Balachandran  and
Yutaka Tai
Ryo Kasuya
Affiliation:
National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya, 463-8560, Japan
Teppei Kikuchi
Affiliation:
Graduate School of Environmental Studies, Tohoku University, 6-6-20, Aramaki, Aoba-ku, Sendai, 980-8579, Japan
Jeyadevan Balachandran
Affiliation:
School of Engineering, University of Shiga Prefecture 2500 Yasaka-cho, Hikone, 522-8533 Japan
Yutaka Tai
Affiliation:
National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya, 463-8560, Japan
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Abstract

An aqueous magnetic suspension was prepared by dispersing amphiphilic co-polymer (ACP) coated monodispersed magnetite nanoparticles (MNPs) synthesized through thermal decomposition of iron(III) acetylacetonate in a mixture of oleic acid and oleylamine. ACP composed of poly (maleic anhydride-alt-1-octadecene) and polyethylene glycol methyl ether was applied to disperse MNPs in water and buffer solution. The average diameter of MNPs increased from 6.6 to 12.5 nm with increasing reaction temperature from 200 to 250°C. Infrared spectra and elemental analysis revealed that the surface modified MNPs contain carboxyl groups originated from oleic acid and ACP. The conjugation of MNPs and bovine serum albumin (BSA) antibody was examined. As a result, the as-synthesized MNPs adsorbed BSA antibody effectively than the surface modified MNPs: the BSA antibody adsorption decreased with increasing cross-linker concentration.

Keywords

oxidebiomedicalchemical synthesis
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1386: Symposium D – Sustainable Synthesis of Nanomaterials , 2012 , mrsf11-1386-d13-02
Copyright
Copyright © Materials Research Society 2012

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References

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