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Synthesis and Characterization of Environmentally Responsive Core-Shell Hydrogel Nanoparticles

Published online by Cambridge University Press:  15 March 2011

Clinton D. Jones ,
Christina Baker  and
L. Andrew Lyon
Clinton D. Jones
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology Atlanta, GA 30332-0400, U.S.A
Christina Baker
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology Atlanta, GA 30332-0400, U.S.A
L. Andrew Lyon
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology Atlanta, GA 30332-0400, U.S.A
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Abstract

We report the synthesis of environmentally responsive hydrogels as nano-sized particles with core-shell morphologies. Composed of co-polymers of N-isopropylacrylamide with various co-monomers, these materials can be designed to render the core and shell responsive to different stimuli or to different magnitudes of the same stimulus. The measured phase transitions reflect the degree to which the two materials interact and thereby modulate the responsivity of the particle as a whole. Characterization of these materials is accomplished via dynamic light scattering and electron microscopy.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 662: Symposia LL/MM/NN/OO – Biomaterials for Drug Delivery & Tissue Engineering , 2000 , NN1.4
Copyright
Copyright © Materials Research Society 2001

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