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SWNT NETWORK for BIOMOLECULE DETECTION

Published online by Cambridge University Press:  01 February 2011

Massood Z. Atashbar ,
Bruce Bejcek  and
Srikanth Singamaneni
Massood Z. Atashbar
Affiliation:
Electrical and Computer Engineering, Western Michigan University, Kalamazoo, MI-49008, USA
Bruce Bejcek
Affiliation:
Department of Biological Sciences, Western Michigan University, Kalamazoo, MI-49008, USA
Srikanth Singamaneni
Affiliation:
Electrical and Computer Engineering, Western Michigan University, Kalamazoo, MI-49008, USA
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Abstract

In this paper we describe a single wall carbon nanotube (SWNT) based biological sensor for the detection of biomolecules using streptavidin and IgG. Two types of sensing mechanisms have been used to demonstrate the ability of carbon nanotubes to form nanoscale biosensors. The first sensing mechanism involves a CNT based conduction sensor in which the decrease in the current was observed when the specific biomolecule was bound. In the second mechanism Quartz Crystal Microbalance (QCM) was used to quantify the mass of the biomolecule bound on the sidewalls of the carbon nanotube. Both sensing mechanisms proved to be efficient and consistent. Immobilization of the biomolecules on the carbon nanotube surface was confirmed by Atomic Force Microscopy.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 858: Symposium HH – Functional Carbon Nanotubes , 2004 , HH14.8
Copyright
Copyright © Materials Research Society 2005

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References

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