Radionuclide migration experiments in fractured granite at the Climax Stock, Nevada Test Site, are needed to compare field and laboratory measured retardation factors to determine whether laboratory studies accurately reflect in situ conditions. Initial field activities have concentrated on hydrological investigations to determine whether the fractures in Climax granite are suitable for migration experiments. A critical question was whether we could isolate a single vertical fracture between two boreholes and establish flow along that fracture from an upper to a lower borehole. Of the ten fractures tested, one fracture would not take water at pressures up to 200 psig for 24 hours. Several fractures were so permeable they accepted water at a rate which exceeded the pumping capacity of the equipment. Other fractures failed to show a connection between the two boreholes. In two fractures, we were able to establish a circulating system with up to 95 percent of the injected water being recovered. Constant pressure injection tests were conducted. Intrinsic permeabilities of 33 and 75 (μm)2 were estimated using a radial nonsteady flow model. These values correspond to effective fracture apertures of 20 and 30 μm respectively. Concurrent with the hydraulic testing activities is a study of the Climax ground-water chemistry. Our analyses show the natural water to be very different in composition from the granite equilibrated water used in laboratory sorption studies. This paper includes the results of the hydrogeological and geochemical investigations, and describes the overall experimental design plans for the radionuclide migration experiments.