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Remineralization of Artificial Dentin Lesions via the Polymer-Induced Liquid-Precursor (PILP) Process

Published online by Cambridge University Press:  13 July 2011

Taili Thula-Mata ,
Anora Burwell ,
Laurie B. Gower ,
Stefan Habelizt  and
Grayson Marshall
Taili Thula-Mata
Affiliation:
Materials Science & Engineering Department, University of Florida, Gainesville, FL 32611, U.S.A.
Anora Burwell
Affiliation:
Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA, U.S.A.
Laurie B. Gower
Affiliation:
Materials Science & Engineering Department, University of Florida, Gainesville, FL 32611, U.S.A.
Stefan Habelizt
Affiliation:
Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA, U.S.A.
Grayson Marshall
Affiliation:
Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA, U.S.A.
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Abstract

Acid-etched dentin samples with a zone of demineralized dentin were remineralized via the polymer-induced liquid-precursor (PILP) process. Poly-L-aspartic acid was used as the polymeric process-directing agent. Samples were incubated in the mineralization solution for 1- 4 weeks. Dentin samples remineralized by the PILP process presented a surface morphology very similar to the intact mineralized dentin’s architecture, in contrast to samples mineralized via the conventional nucleation and growth method (without polymer additive), which led to a superficial crust of randomly organized mineral crystals. Energy dispersive x-ray spectroscopy analysis of the PILP-mineralized samples showed the presence of calcium and phosphate ions at high levels. Since no hydroxyapatite (HA) clusters were observed on the surface of the PILP-mineralized samples, we could conclude the signal was produced from the mineral embedded within the dentin matrix. TEM and diffraction analyses suggest that both intrafibrillar and interfibrillar remineralization occurred in the demineralized dentin matrix.

Keywords

amorphousbiomimetic (chemical reaction)crystal growth
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1355: Symposium JJ – Biological Hybrid Materials for Life Sciences , 2011 , mrss11-1355-jj08-01
Copyright
Copyright © Materials Research Society2011

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