Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-29T09:41:26.938Z Has data issue: false hasContentIssue false
  • English
  • Français

Optical Characterization of Biological and Other Systems

Published online by Cambridge University Press:  17 March 2011

Alexandra G. Bezrukova
Alexandra G. Bezrukova*
Affiliation:
Department of Bioengineering, Faculty of Medical Physics and Bioengineering, St.Petersburg State Technical University (Polytechnic Institute), Polytekhnicheskaya str. 29, St.Petersburg 195 251, RUSSIA
Get access

Abstract

Multiparametric optical analysis (MOA) can provide further progress in characterization and on-line control of biological and other disperse systems with nanoparticles as the disperse phase in various dispersive media. MOA includes the nondestructive simultaneous testing of disperse systems by different compatible optical methods such as refractometry, absorption, fluorescence, light scattering (integral and differential, static and dynamic, unpolarized and polarized). For the solution of inverse optical problems various techniques can be applied. By optical methods it is possible to determine parameters of disperse system's state (mean equivalent diameter and number of particles, mean refractive index and mass of disperse phase, number and mass distributions) and parameters of particle's structure. This paper is devoted to characterization of biological particles that can be approximated as bilayered spheres (blood-substitutes, liposomes, etc.) and to polarization measurements of disperse systems (viruses, bacterial cells, etc.) which can help to develop on-line control of environment.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 711: Symposia FF/GG/HH – Advanced Biomaterials--Characterization, Tissue Engineering and Complexity , 2001 , FF7.9.1
Copyright
Copyright © Materials Research Society 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Bezrukova, A.G. in Remote Sensing of Vegetation and Water, and Standardization of Remote Sensing Methods, edited by Cecchi, G., Lamp, T., Reuter, R. and Weber, K., Proc. of SPIE - The International Society for Optical Engineering, 3107, pp. 298–304(1997).Google Scholar
2. Frenkel, S.Ya., Vestnik of Russian Academy of Natural Sciences N2(2), 162(1998) - in Russian.Google Scholar
3. Bezrukova, A.G., Rozenberg, O.A., Bull. Experimental Biology and Medicine 91, N4, 506 (1981). - in Russian.Google Scholar
4. Kuznetsova, I.N., Art.Cells, Blood-Subs., and Immob. Biotech. 26(2), 181(1998).Google Scholar
5. Kuznetsova, I.N., Bezrukova, A.G., Lopatin, V.N., Parshin, A.V., Biofizika 33, 126 (1988) - in Russian.Google Scholar
6. Kuznetsova, I.N., Bezrukova, A.G., Kolloidnii Zhurnal 52, 132 (1990)- in Russian.Google Scholar
7. Bezrukova, A. G., Katushkina, N.V., Parshin, A.V., Efimov, S.V., Mischenko, B.S., Kolikov, V. M., Voprosi virusologii 37, N 3, IV (1992) - in Russian.Google Scholar
8. Efimov, S.V., Bezrukova, A.G., Katushkina, N.V., Kolikov, V.M., Kolloidnii Zhurnal 49, 345 (1987) - in Russian.Google Scholar
9. Shifrin, K.S., Tonna, G., Advances in Geophysics 34, 175 (1993).Google Scholar
10. Klenin, V.J., Thermodynamics of Systems Containing Flexible-Chain Polymers, (Elsevier, 1999), p. 850.Google Scholar
11. Hulst, H.C.van de,Light Scattering by Small Particles (Wiley, New York, 1957).Google Scholar
12. Bohren, C.F. and Huffman, D.R., Absorption and Scattering of Light by Small Particles (Wiley, New York, 1983).Google Scholar
13. Sidko, F.Ya., Lopatin, V.N. and Paramonov, L.E., Polarization Characteristics of Biological Particle Suspensions, (Novosibirsk, Nauka, 1990), p.120 - in Russian.Google Scholar
14. Light Scattering by Nonspherical Particles. Theory, Measurements and Applications. Edited by Mishchenko, Michael I., Hovenier, Joachim W., Travis, Larry D. (AP, 1999), p.690.Google Scholar
15. Shchyogolev, S. Yu., Journal of Biomedical Optics 4 (4), 490–503 (October 1999).Google Scholar
16. Klyubin, V.V., Braginskaya, T.G., Kuznetsov, A.S., Bezrukova, A.G., Kolikov, V.M., Kolloidnii zhurnal 51, 376–378 (1989)- in Russian.Google Scholar
17. Goltsman, F.M., Statistical models of interpretation, (Moscow, 1971), p.327. - in Russian.Google Scholar