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Novel Growth of Biodegradable Thin Films via Matrix Assisted Laser Processing

Published online by Cambridge University Press:  15 February 2011

A.L. Mercado ,
J.M. Fitz-Gerald ,
R. Johnson  and
J.D. Talton
A.L. Mercado
Affiliation:
University of Virginia, Dept of Materials Science and Engineering
J.M. Fitz-Gerald
Affiliation:
University of Virginia, Dept of Materials Science and Engineering
R. Johnson
Affiliation:
University of Virginia, Dept of Chemistry Charlottesville, VA 22904-4745
J.D. Talton
Affiliation:
Nanotherapeutics Inc, Alachua, FL
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Abstract

The ability to controllably deposit polymers onto flat or curved surfaces in a quasi-dry environment while retaining native-like structure is of extreme importance to the medical and microelectronics communities. Current applications range from protective and conformal coatings for microelectronics to sustained drug delivery platforms in the pharmaceutical industry. In this research, biodegradable thin films of poly(DL-lactide-co-glycolide) (PLGA), were deposited onto flat substrates of Si and NaCl using a pulsed excimer laser, (λ= 248 nm) with fluences ranging from 0.1 – 1.0 J/cm2 via matrix assisted pulsed laser evaporation (MAPLE). Results are shown from scanning electron microscopy (SEM) to study morphological features and Fourier Transform Infrared Spectroscopy (FTIR), and Nuclear Magnetic Resonance (NMR) to measure chemical structure compared to original PLGA.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 780: Symposium Y – Advanced Optical Processing of Materials , 2003 , Y4.4
Copyright
Copyright © Materials Research Society 2003

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References

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