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Non-Invasive Monitoring of Acute Intracranial Mass Lesions Using Ultrasonic Fingerprinting

Published online by Cambridge University Press:  10 February 2011

P. B. Nagy ,
W. S. Rosenberg  and
L. M. Stankovits
P. B. Nagy
Affiliation:
Department of Aerospace Engineering, University of Cincinnati, Cincinnati, OH 45221-0070
W. S. Rosenberg
Affiliation:
Department of Neurosurgery, University of Cincinnati, Cincinnati, OH 45267-0665
L. M. Stankovits
Affiliation:
Department of Neurosurgery, University of Cincinnati, Cincinnati, OH 45267-0665
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Abstract

Potentially dangerous neurological changes in shock-trauma patients are currently monitored by computer-aided X-ray tomography which is prohibitively expensive and even dangerous for long-term, e.g., comatose, patients. By ultrasound, only low-frequency “diffuse” ultrasonic inspection is feasible through the skull so that the details are irreversible lost in the essentially random scattering process. In order to overcome this inherent limitation, we adapted a continuous computer-controlled ultrasonic monitoring system based on the ultrasonic fingerprinting method originally developed for materials characterization purposes in the nuclear, civil engineering, and aerospace industries. An ultrasonic detector directed at the general area of interest can be used to record and repeatedly update the personal signature of the patient, which is then used as an “ultrasonic fingerprint.” Any abrupt change in this signature indicates the immediate need for further investigation by CT or other sophisticated diagnostic tools. Experimental studies were conducted on both a human skull/gelatin phantom and 5 intact human cadavers. Ultrasonic fingerprinting could detect the secondary effects of volumetric changes occurring at multiple locations and the average detectable volumes of mass lesions were found to be lower than indications for surgical intervention.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 503: Symposium JJ – Nondestructive Characterization of Materials in Aging Systems , 1997 , 249
Copyright
Copyright © Materials Research Society 1998

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References

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