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Neuronal Outgrowth Guidance on Patterned Organic Films

Published online by Cambridge University Press:  15 February 2011

M. M. Matsuzawa ,
V. Krauthamer  and
R.S. Potember
M. M. Matsuzawa
Affiliation:
Applied Physics Laboratory, The Johns Hopkins University, Laurel, MD 20723 Frontier Research Program, RIKEN, Wako, Saitama, 351-01, Japan
V. Krauthamer
Affiliation:
Electrophysics Branch, Food and Drug Administration, Rockville, MD 20852
R.S. Potember
Affiliation:
Applied Physics Laboratory, The Johns Hopkins University, Laurel, MD 20723
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Abstract

Glass substrates were modified with organic thin films to guide the outgrwoth of cultured neurons dissociated from the central nervous system. Embryonic hippocampal neurons, grown on these modified substrates, developed a morphology by following the surface geometries and they formed contacts with each other. We are now investigating technical procedures for forming physiological synapses using goldfish retinal neurons in culture.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 530: Symposium CC – Biomaterials Regulating Cell Function & Tissue Development , 1998 , 59
Copyright
Copyright © Materials Research Society 1998

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References

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