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Nanostructured Selenium for Preventing Biofilm Formation on Medical Devices

Published online by Cambridge University Press:  12 January 2012

Qi Wang  and
Thomas J. Webster
Qi Wang
Affiliation:
Department of Chemistry, Brown University, Providence, RI02906, U.S.A.
Thomas J. Webster
Affiliation:
School of Engineering, Brown University, Providence, RI02906, U.S.A.
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Abstract

Biofilms are a common cause of persistent infections on medical devices as they are easy to form and hard to treat. Selenium and its compounds are considered to be a novel material for a wide range of applications including anticancer applications and antibacterial applications. The objective of this study was to coat selenium nanoparticles on the surface of polycarbonate medical devices and examine their effectiveness at preventing biofilm formation. The results of this in vitro study showed that the selenium coating significantly inhibited Staphylococcus aureus growth on the surface of polycarbonate after 24 hours. Thus, this study suggests that coating polymers with nanostructured selenium is a fast and effective way to reduce bacteria functions leading to medical device infections.

Keywords

biomaterialSepolymer
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1415: Symposium HH/II/TT – MEMS, BioMEMS and Bioelectronics–Materials and Devices , 2012 , mrsf11-1415-ii03-13
Copyright
Copyright © Materials Research Society 2012

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References

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