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A Multifunctional Microgripper Capable of Simultaneous Single Cell Manipulation and Associated Ion Sensing

Published online by Cambridge University Press:  30 July 2012

Rachael Daunton ,
Andrew J. Gallant ,
Ritu Kataky  and
David Wood
Rachael Daunton
Affiliation:
Department of Chemistry, Durham University, South Road, Durham DH1 3LE UK School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK
Andrew J. Gallant
Affiliation:
School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK
Ritu Kataky
Affiliation:
Department of Chemistry, Durham University, South Road, Durham DH1 3LE UK
David Wood
Affiliation:
School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK
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Abstract

The successful modification of the tips of a cellular microgripper into ion selective electrodes capable of sensing calcium ions at concentrations as low as 8x10-5 M is described. The modification involves applying the process of adding the components of all solid state ion selective electrodes. Specifically, poly(3,4-ethylenedioxythiophene) (PEDOT) is added to a gold electrode protruding from the microgripper tip; this is then coated with a poly(vinyl chloride) PVC based calcium selective membrane. Excellent Nernstian response was observed from our devices, with calibration slopes of 29.5 ± 2.5 mV/dec.

Keywords

sensormicroelectro-mechanical (MEMS)electrodeposition
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1463: Symposium QQ – Mechanobiology of Cells and Materials , 2012 , mrss12-1463-qq03-03
Copyright
Copyright © Materials Research Society 2012

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References

REFERENCES

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