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Molecular Imprinted Hydrogels in Drug Delivery Applications

Published online by Cambridge University Press:  14 May 2015

Jeffrey S. Bates ,
Luke R. Whitson ,
Kelan M. Albertson ,
Nathan S. Hickerson ,
Patrick E. Nichols ,
Bethany E. Larson  and
Taylor D. Sparks
Jeffrey S. Bates
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Luke R. Whitson
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Kelan M. Albertson
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Nathan S. Hickerson
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Patrick E. Nichols
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Bethany E. Larson
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
Taylor D. Sparks
Affiliation:
Materials Science and Engineering, University of Utah, 122 S. Central Campus Drive, Room 304, Salt Lake City, UT 84112
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Abstract

Molecular imprinting is the process by which molecules are imprinted into the matrix of a material through non-covalent bonding, including hydrogen bonding and van der Waals interactions. In this study hydrogels were imprinted with glaucoma medication with the purpose of creating a reusable ocular drug delivery device with reversible binding sites. The material was synthesized and tested with UV-Vis spectroscopy to determine the concentration of the released drug after twelve hours in distilled water. Modifications were made to the polymer to explore methods required for the proper delivery of the drug over an adequate period of time.

Keywords

biomedicalpolymerpolymerization
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1797: Symposium KK – Nanomaterials in Translational Medicine , 2015 , mrss15-2132190
Copyright
Copyright © Materials Research Society 2015 

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References

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