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Microstructured Bioactive Interfaces using Piezoelectric Ink Jet Technology

Published online by Cambridge University Press:  01 February 2011

Anand Doraiswamy ,
Cerasela Z. Dinu ,
Jan Sumerel ,
Douglas B. Chrisey  and
Roger J. Narayan
Anand Doraiswamy
Affiliation:
[email protected], University of North Carolina, Biomedical Engineering, 152 MacNider Hall, CB 57575, Chapel Hill, NC, 27599-7575, United States
Cerasela Z. Dinu
Affiliation:
Rensselaer Polytechnic Institute, Troy, NY, 12180, United States
Jan Sumerel
Affiliation:
[email protected], Fujifilm Dimatix, 2230 Martin Avenue, Santa Clara, CA, 95050, United States
Douglas B. Chrisey
Affiliation:
[email protected], Rensselaer Polytechnic Institute, Troy, NY, 12180, United Stat es
Roger J. Narayan
Affiliation:
[email protected], University of North Carolina, Chapel Hill, NC, 27599-7575, United States
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Abstract

We have demonstrated microscale patterning of biotin and streptaividin proteins using an athermal rapid prototyping process based on piezoelectric inkjet technology. A MEMS-based piezoelectric actuator was used to dispense picoliter quantities of fluid through micron-sized nozzles. Atomic force microscopy and Fourier infrared spectroscopy studies were performed on CAD/CAM deposited proteins that were prepared using several firing voltages. Our results indicate that piezoelectric inkjet deposition is a powerful non-contact, non-destructive process for developing high-throughput biological microarrays for use in biosensing, cell culturing, and tissue engineering.

Keywords

biomaterialbiologicalbiomedical
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 950: Symposium D – Biosurfaces and Biointerfaces , 2006 , 0950-D15-23
Copyright
Copyright © Materials Research Society 2007

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References

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