Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-27T01:59:13.340Z Has data issue: false hasContentIssue false

Manipulation of 10 – 40 μm Diameter Cells Using a Thermally Actuated Microgripper

Published online by Cambridge University Press:  29 May 2012

Rachael Daunton
Affiliation:
School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK Department of Chemistry, Durham University, South Road, Durham DH1 3LE UK
Andrew J. Gallant
Affiliation:
School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK
David Wood
Affiliation:
School of Engineering and Computing Sciences, Durham University, South Road, Durham DH1 3LE UK
Get access

Abstract

This work presents the successful fabrication of a thermally actuated U-shaped microgripper that has been specially designed to enable low voltage operation for bidirectional in plane deflection. The microgripper tips are carefully designed to match the biological species being manipulated, which has been demonstrated by the successful manipulation of 10 – 40 μm diameter particles used to simulate biological cells.

Type
Articles
Copyright
Copyright © Materials Research Society 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

[1] Solano, B., Gallant, A. J., Greggains, G. D., Wood, D., and Herbert, M., (2009) Low voltage microgripper for single cell manipulation, Adv. Sci. Tech., 57, pp. 6772 10.4028/www.scientific.net/AST.57.67Google Scholar
[2] Lin, G., Kim, C. J., Konishi, S. and Fujita, H., (1995) “Design, fabrication and testing of a C-shape actuatorProc. Transducers ’95 Eurosensors IX, Stockholm, Sweden, pp. 416419 Google Scholar
[3] Chronis, N. and Lee, L., (2005) Electrothermally Activated SU-8 Microgripper for Single cell manipulation in Solution, J. Microelectromechanical systems, 14, pp. 857863 10.1109/JMEMS.2005.845445Google Scholar
[4] Matmat, M., Al Ahmad, M., Escriba, C., Soulimane, S., Marty, A. and Fourniols, J. Y., (2008) “Thermo-electro-mechanical V-shaped actuator design and simulations” Proc 9th Int. Conf., Freibury im Breisgau, Germany, pp. 14 Google Scholar
[5] Solano, B, Gallant, A. J. and Wood, D., (2009) “Design and optimization of a microgripper: Demonstration of biomedical applications using the manipulation of oocytes” Proc. Design, test, integration and packaging of MEMS/MOEMS, Rome, Italy, pp. 6165 Google Scholar
[6] del Campo, A. and Greiner, C., (2007) SU-8: a photoresist for high aspect ratio and 3D submicron lithography, J. Micromech. Microeng., 17, pp. R81R95 10.1088/0960-1317/17/6/R01Google Scholar
[7] Cheng, C. M., and Chen, R. H., (2001) Development behaviours and microstructure quality of downward development in deep x-ray lithography, J. Micromech. Microeng., 11, pp. 6926 10.1088/0960-1317/11/6/310Google Scholar
[8] Daunton, R., Gallant, A. J. and Wood, D., (2012) Manipulation of exposure dose parameters to improve production of high aspect ratio structures using SU8, J. Micromech. Microeng. (accepted)10.1088/0960-1317/22/7/075016Google Scholar
[9] Daunton, R., Gallant, A. J., Wood, D. and Kataky, R., (2011). A thermally actuated microgripper as an electrochemical sensor with the ability to manipulate single cells, Chem. Commun, 47, pp. 64466448.10.1039/c1cc11904dGoogle Scholar
[10] Daunton, R., Gallant, A. J., Kataky, R. and Wood, D., (2012), A multifunctional microgripper capable of simultaneous single cell manipulation and associated ion sensing, Proc. Materials Research Society Meeting, San Francisco, USA, (accepted)Google Scholar