Low cost fabrication is key to the successful introduction of organic electronics and roll to roll manufacturing processes. We propose here that extending flexography into the micron size resolution regime may provide an economical commercialization path for plastic devices. Flexography is a high-speed technique commonly used for printing onto very large area flexible substrates.[1] Although low resolution and poor registration are characteristics of today's flexographic process, it has many similarities with soft lithographic techniques. This work shows that large, (12”×12”) high-resolution printing plates appropriate for use on small tag and label flexographic presses can be prepared using simple and inexpensive flexographic compatible processes. We illustrate the use of these plates for three representative soft lithographic processes: microcontact printing, replica molding, and phase shift lithography.