Hostname: page-component-745bb68f8f-grxwn Total loading time: 0 Render date: 2025-01-28T23:22:40.128Z Has data issue: false hasContentIssue false
  • English
  • Français

Influence of Different Capillary Geometries on the Plug Distortion in Hybrid Micro Channels

Published online by Cambridge University Press:  01 February 2011

Lars Storsberg ,
Lars Schöler ,
Konstantin Seibel ,
Heiko Schäfer ,
Marcus Walder ,
René Johannes Püschl ,
Bernd Wenclawiak  and
Markus Böhm
Lars Storsberg
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
Lars Schöler
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
Konstantin Seibel
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
Heiko Schäfer
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
Marcus Walder
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
René Johannes Püschl
Affiliation:
[email protected], University of Siegen, Analytical Chemistry, Adolf Reichwein Str. 2-4, Siegen, N/A, Germany
Bernd Wenclawiak
Affiliation:
[email protected], University of Siegen, Analytical Chemistry, Adolf Reichwein Str. 2-4, Siegen, N/A, Germany
Markus Böhm
Affiliation:
[email protected], University of Siegen, Institute for Microsystem Technologies, Hölderlinstr. 3, Siegen, N/A, Germany
Get access

Abstract

The plug distortion for on-chip capillary zone electrophoresis systems with rectangular separation channels, manufactured in a hybrid layer system with different material properties of the vertical and the horizontal walls has been examined. Experimental data and simulation results indicate that plug widening caused by different values of the #950;-potential of the walls in contact with the fluid depends strongly on the aspect ratio of the channel cross section. If the height to width ratio is much greater or much smaller than 1, as is often the case for commonly used labchip architectures, plug widening may be negligible. The difference of the #950;-potentials between the vertical and the horizontal side walls has been determined from the shape of the plug edges. For an architecture using glass for the top and bottom walls, but SU-8 for the side walls, the difference of the #950; potentials was measured to be on the order of only 2.4 mV for a pH of 9.2, suggesting that such device architectures may be used for on-chip electrophoresis analysis without uniform coating of the channel inside for less demanding applications.

Keywords

electromigrationfluidicspolymer
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1004: Symposium P – Materials and Strategies for Lab-on-a-Chip-Biological Analysis, Microfactories, and Fluidic Assembly of Nanostructures , 2007 , 1004-P03-21
Copyright
Copyright © Materials Research Society 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Hertzog, D., Santiago, J., Bakajin, O., Proc. of µ TAS Confer., 1:539–541 (2004).Google Scholar
2. Schönfeld, F., Hardt, S., Proc. of µ TAS Confer., 1:67–69 (2005).Google Scholar
3. Chen, C.-H., Santiago, J., Journal of Microelectromechanical Systems, 11:672–683 (2002).Google Scholar
4. Studer, V., Pépin, A., Chen, Y., Ajdari, A., Microelectronic Engineering, 915:61–62 (2002).Google Scholar
5. Wang, Z., Kutter, J. P., Wolff, A., Proc. of µ TAS Confer., 1:460–462 (2004).Google Scholar
6. Kamei, T., Paegel, B. M., Scherer, J.R., Skelley, A. M., Anal. Chem., 75:5300–5305 (2003).Google Scholar
7. Trush, E., Levi, O., Cook, L. J., Deich, J. et al. , Sens. Actuators B, 105:393–399 (2005).Google Scholar
8. Verpoorte, E., Electrophoresis, 23:677–712 (2002).Google Scholar
9. Kajjout, M., Rolando, C., Gac, S. Le, Proc. of µ TAS Confer., 2:267–269 (2004).Google Scholar
10. Chemnitz, S., Schäfer, H., Schuhmacher, S., Koziy, V., Fischer, A., Meixner, A., Erhardt, D., Boehm, M., Proc. SPIE Conference, vol. 5116-5119, pp. 782–789 (2003).Google Scholar
11. Butt, H. J., Graf, K., Kappl, M., Physics and Chemistry of Interfaces, (Wiley-VCH, 2003).Google Scholar
12. Ermakov, S. V., Jacobson, S. C., and Ramsey, J.M., Analytical Chemistry, 72: p. 3512–3517 (2000).Google Scholar
13. Patankar, N. A., and Hu, H.H., Analytical Chemistry, 70: p. 1870–1881 (1998).Google Scholar
14. Sikanen, T., Tuomikoski, S., Ketola, R. A., Kostiainen, R., Franssila, S., Kotiaho, T., Lab Chip, 5:888–986 (2005).Google Scholar