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In vitro Apatite Deposition and Biodegradation of Porous Gelatin-Silicate Hybrids Derived from Sol-Gel Process
Published online by Cambridge University Press: 01 February 2011
Abstract
Ca (II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca (II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.
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- Copyright © Materials Research Society 2000