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Fracture Toughness Testing of In Vivo Aged Biomaterials

Published online by Cambridge University Press:  22 February 2011

R. M. Pilliar ,
D. F. Williams  and
R. Vowles
R. M. Pilliar
Affiliation:
Faculty of Dentistry, University of Toronto, Toronto, Canada, M5G 1G6
D. F. Williams
Affiliation:
Department of Dental Sciences, University of Liverpool, Pembroke Place, Liverpool, England, L69 3BX
R. Vowles
Affiliation:
Department of Dental Sciences, University of Liverpool, Pembroke Place, Liverpool, England, L69 3BX
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Abstract

Although mechanical property characterization of materials for loadbearing implant applications is recognized as a necessary prerequisite to their in vivo use, tests are usually restricted to in vitro situations becaus-of specimen size and cost limitation. Thisstid7'Jescribes a fracture toughness test that uses small specimens that can be conveniently placed in intermuscular positions in laboratory rats. The method is illustrated for the evaluation of two orthopaedic biomaterials namely bone cement and a filled composite (hydroxyapatite-filled polyethylene). The results indicated little mechanical degradation of the bone cement after 120 days in vivo but a significant change in the filled polyethylene composite after only 70 days in vivo.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 55: Symposium G – Biomedical Materials , 1985 , 369
Copyright
Copyright © Materials Research Society 1986

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References

REFERENCES

1. Fahr, A., Brown, R.F., Day, D.E., J. Biomed. Mater. Res. 17 (3), 395–410 (1983).Google Scholar
2. Bundy, K.J., Marek, M., Hochman, R.F., J. Biomed. Mater. Res., 17 (3), 467–487 (1983).CrossRefGoogle Scholar
3. Liebert, T.C., Chartoff, R.P., Cosgrove, S.L., McCuskey, R.S., J. Biomed. Mater. Res., 10 (6), 939–951 (1976).Google Scholar
4. Miller, M.D., Williams, D.F., Biomaterials, 5, 365–368 (1984).CrossRefGoogle Scholar
5. Rostoker, W., Lereim, P., Galante, J. O., J. Biomed. Mater. Res., 13 (3), 365–370 (1979).Google Scholar
6. Jacobs, M.L., Black, J., J. Biomed. Mater. Res. Symp., 9 (4), 221–225 (1975).Google Scholar
7. Amstutz, H.C., Lodwig, M., J. Biomed. Mater. Res., 10 (1), 25–31 (1975).Google Scholar
8. Freitag, T.A., Cannon, S.L., J. Biomed. Mater. Res., 10 (5), 805–826 (1976).Google Scholar
9. Stark, C.F., J. Biomed. Mater. Res., 13 (2), 339–342 (1979).Google Scholar
10. Sih, G.C., Berman, A.T., J. Biomed. Mater. Res., 14 (11), 311–324 (1980).Google Scholar
11. Robinson, R.P., Wright, T.M., Burstein, A.H., J. Biomed. Mater. Res., 15 (2), 203–208 (1981).Google Scholar
12. Lloyd, C.H., J. Oral Rehab., 11, 393–398 (1984).Google Scholar
13. Goldman, M., J. Biomed. Mater. Res., 19 (7), 771–783 (1985).Google Scholar
14. Roberts, J.C., Powers, J.M., Craig, R.G., J. Dent. Res., 56 (7), 748–753 (1977).Google Scholar
15. Pilliar, R.M., Smith, D.C., Maric, B., Fracture toughness of dental composites determined using the short rod fracture toughness test, submitted for publication to J. Dent. Res. (1986).Google Scholar
16. Bonfield, W., Behiri, J.C., Doyle, C., Bowman, J., Abram, J., in Biomaterials and Biomechanics, edited by Ducheyne, P., Van der Perre, G., Aubert, A.E. (Elsevier Science Publishers, B.V., Amsterdam, 1984).Google Scholar
17. Barker, L.M., Eng. Fracture Mech., 9, 361–369 (1977).Google Scholar
18. Pilliar, R.M., Vowles, R., Williams, D.F., Fracture toughness testing of biomaterials: mini-short rod fracture toughness specimen design, submitted for publication to J. Biomed. Mater. Res. (1985).Google Scholar
19. Bubsey, R.T., Mung, D., Pierce, W.S., Shannon, J.L. Jr, Int. J. Fract., 18, 125–133 (1982).Google Scholar
20. Barker, L.M., Int. J. Fract., 15, 515–536 (1979).Google Scholar
21. Oppenheimer, B.S., Oppenheimer, E.T., Donishefsky, I., Stout, A.P., Eirich, F.R., Cancer Res., 15, 333 (1955).Google Scholar
22. de Groot, K., Biodegradable Ceramics in Biocompatibility of Clinical Materials, Vol. I, edited by Williams, D.F. (CRC Press, Inc., Boca Raton, 1981).Google Scholar
23. Abram, J., Bowman, J., Behiri, J.C., Bonfield, W., Plastics and Rubber Processing and Applications, 4, 261–269 (1984).Google Scholar