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Fast Formation of Biomimetic Ca-P Coatings on Ti6Al4V

Published online by Cambridge University Press:  10 February 2011

F. Barrère ,
P. Layrolle ,
C. A. van Blitterswijk  and
K. de Groot
F. Barrère
Affiliation:
IsoTis BV, Prof. Bronkhostlaan 10, 3723 MB Bilthoven, The Netherlands Twente University, The Netherlands
P. Layrolle
Affiliation:
IsoTis BV, Prof. Bronkhostlaan 10, 3723 MB Bilthoven, The Netherlands
C. A. van Blitterswijk
Affiliation:
IsoTis BV, Prof. Bronkhostlaan 10, 3723 MB Bilthoven, The Netherlands Twente University, The Netherlands
K. de Groot
Affiliation:
IsoTis BV, Prof. Bronkhostlaan 10, 3723 MB Bilthoven, The Netherlands Leiden University, The Netherlands
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Abstract

The aim of this study was to accelerate the formation of biomimetic Calcium-Phosphate (Ca-P) coatings on Ti6Al4V by using a 5 times more concentrated Simulated Body Fluid (SBFx5) than the regular SBF. The production of SBFx5 was possible by decreasing the pH of the solution to approximately 6 with CO2 gas. The release of this mildly acidic gas allowed the formation of a Ca-P film after 4h of immersion at pH=6.8. The structure of this coating was an amorphous carbonated Ca-P. In addition, our experiments showed that the presence of Mg2+ was absolutely necessary for the Ca-P coating formation on Ti6Al4V substrate. Mg2+ is a crystal growth inhibitor and favored the heterogeneous nucleation. Furthermore, depth profile X-Ray Photoelectron Spectroscopy showed that Ca-P nucleation on the passive Titanium oxide (TiO2) passive layer was initiated by Ca2+ and Mg2+. The attachment of this Ca-P coating resulted probably from chemical bonds such as P-O-Ti and Ca-O-Ti. Ca was more present at the coating/substrate interface than P. Thereby Ca-O-Ti seems to be favored.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 599: Symposium DD – Mineralization in Natural & Synthetic Biomaterials , 1999 , 135
Copyright
Copyright © Materials Research Society 2000

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