Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-29T07:38:55.818Z Has data issue: false hasContentIssue false
  • English
  • Français

Evaluation of Thermal Properties and Physical Aging as Function of the Pendent Chain Length in Tyrosine-Derived Polycarbonates, a Class of New Biomaterials

Published online by Cambridge University Press:  21 February 2011

Varawut Tangpasuthadol ,
Adi Shefer ,
Kimberly A. Hooper  and
Joachim Kohn
Varawut Tangpasuthadol
Affiliation:
Department of Chemistry, Rutgers University, Piscataway, NJ 08855–0939
Adi Shefer
Affiliation:
Department of Chemistry, Rutgers University, Piscataway, NJ 08855–0939
Kimberly A. Hooper
Affiliation:
Department of Chemistry, Rutgers University, Piscataway, NJ 08855–0939
Joachim Kohn
Affiliation:
Department of Chemistry, Rutgers University, Piscataway, NJ 08855–0939
Get access

Extract

Tyrosine-derived polycarbonates are currently in preclinical evaluations for biomedical applications. Although physical aging can significantly alter a wide range of polymer properties, physical aging is has rarely been investigated for biomedical polymers. A series of four tyrosinederived polycarbonates was used as a model system to study the effect of polymer structure on the enthalpy relaxation kinetics.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 394: Symposium Z – Polymers in Medicine and Pharmacy , 1995 , 143
Copyright
Copyright © Materials Research Society 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Ertel, S. I. and Kohn, J., J. Biomed. Mater. Res., 28, 919, (1994).Google Scholar
2. Coffey, D., Dong, Z., Goodman, R., Israni, A., Kohn, J. and Schwarz, K. O., presented at the Symposium on Polymer Delivery Systems at the Spring Meeting of the American Chemical Society, San Fransisco, (1992).Google Scholar
3. Zhou, J., Ertel, S. I., Buettner, H. M. and Kohn, J., 20th Annual Meeting of the Society for Biomaterials, p. 371, Boston MA, Society for Biomaterials, Minneapolis, MN, (1994).Google Scholar
4. Celli, A. and Scandola, M., Polymer, 33(13), 2699, (1992).Google Scholar
5. Pulapura, S. and Kohn, J., Biopolymers, 32, 411, (1992).Google Scholar
6. Bron, S. and Kohn, J., in: Proceed. Am. Chem. Soc., Div. Polym. Mat. Sci. Eng., p. 37, Vol. 69, American Chemical Society, Washington, DC, (1993).Google Scholar
7. Bron, S., Fiordeliso, J. and Kohn, J., IEEE 19th Annual Northeast Bioengineering Conference, p. 145, (Li, J. K.-J. and Reisman, S. S., ed.), Newark, NJ, (1993).Google Scholar
8. Bauwens-Crowet, C. and Bauwens, J.-C., Polymer, 27, 709, (1986).Google Scholar
9. Cheng, S. Z. D., Heberer, D. P., Janimak, J. J., Lien, S. H.-S. and Harris, F. W., Polymer, 32, 2053, (1991).Google Scholar
10. Montserrat, S., J. Polym. Sci., Polym. Phys., 32, 509, (1994).Google Scholar
11. Yoshida, H. and Kobayashi, Y., J. Macromol. Sci. - Phys., B 21(4), 565, (1982).Google Scholar
12. Cowie, J. M. and Ferguson, R., Macromolecules, 22, 2312, (1989).Google Scholar
13. Cowie, J. M. G. and Ferguson, R., Macromolecules, 22, 2307, (1989).Google Scholar