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Enhanced Osteoblast Adhesion on a Novel Hydroxyapatite Coating

Published online by Cambridge University Press:  15 February 2011

Michiko Sato ,
Elliott B. Slamovich  and
Thomas J. Webster
Michiko Sato
Affiliation:
School of Materials Science and Engineering
Elliott B. Slamovich
Affiliation:
School of Materials Science and Engineering
Thomas J. Webster
Affiliation:
School of Materials Science and Engineering
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Abstract

Plasma spray deposition of hydroxyapatite (HA) onto a titanium implant involves high temperatures that may alter HA crystallinity and induce cracks in the coating. For this reason, the objective of this study was to design a novel HA coating material and method. Titanium was coated with HA, titania, and Poly (dl-lactic-glycolic acid) (PLGA) using sol-gel processing. The biocompatibility of the HA coating in the present study was compared to that of a plasmasprayed HA coating. Results of this study showed that osteoblast adhesion was promoted more in the HA coating proposed in this study than on the plasma-sprayed HA coating. In addition, hydrothermal treatment of the coating appeared to improve the biocompatibility of the HA coating. Since osteoblast adhesion is a necessary requirement for increased bonding of an implant to juxtaposed bone, these results support that hydrothermally sol-gel processed HA may be an optimal implant coating material and method.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 774: Symposium O – Materials Inspired by Biology , 2003 , O7.33
Copyright
Copyright © Materials Research Society 2003

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References

1. Søballe, K. Overgaard, S. Hansen, E S. Lind, M., Bunger, C. J. Long-Term Eff. Med. Implt. 9, 131 (1999).Google Scholar
2. Sun, L. Berndt, C. C. Gross, K. A. Kucuk, A. J. Biomed. Mater. Res. 58, 570 (2001)Google Scholar
3. Porter, A.E. Hobbs, L.W. Rosen, V. B. Spector, M. Biomaterials 23, 725 (2002)Google Scholar
4. Cleries, L. Fernandez-Pradas, J.M., Sardin, G. Morenza, J.L. Biomaterials 19, 1483 (1998).Google Scholar
5. Liu, D.M. Troczynski, T. Hakimi, D. J. Mater. Sci. Med. 13, 657 (2002)Google Scholar
6. Liu, D.M. Troezynski, T. Tseng, W.J. Biomaterials 22, 1721 (2001)Google Scholar
7. Fukumoto, S. Nippon Rinsho 60, 57 (2002)Google Scholar