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Elaboration and Evaluation of Membranes from Biopolymers as Delivery System of Plant Extracts

Published online by Cambridge University Press:  01 February 2011

Rodríguez-García A
Affiliation:
Institute of Biotechnology, Faculty of Biological Science, Autonomous University of Nuevo Leon. Pedro de Alba y Av. Manuel L. Barragan S/N. Cd. Universitaria. San Nicolas de los Garza, N.L. CP. 66450. Mexico
Luis J. Galán-Wong L.J.
Affiliation:
Institute of Biotechnology, Faculty of Biological Science, Autonomous University of Nuevo Leon. Pedro de Alba y Av. Manuel L. Barragan S/N. Cd. Universitaria. San Nicolas de los Garza, N.L. CP. 66450. Mexico
Arévalo-Niño K.*
Affiliation:
Institute of Biotechnology, Faculty of Biological Science, Autonomous University of Nuevo Leon. Pedro de Alba y Av. Manuel L. Barragan S/N. Cd. Universitaria. San Nicolas de los Garza, N.L. CP. 66450. Mexico
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Abstract

Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are considered key pathogens in periodontitis that is the principal cause of tooth loss in adults. The treatment of periodontal disease consists on the use of chemicals which can alter oral microbiota and have undesirable side-effects such as vomiting, diarrhea and tooth staining

At recent years, the use of natural sources like biomaterials such as biopolymers and plant extracts are enjoying great popularity. Chitosan and pullulan are polymers that have been proposed due to their favorable properties such as biocompatibility, biodegradability, adhesion ability and nontoxicity

The aim of this study was to develop films from chitosan and pullulan containing plant extracts as delivery system and determine the in vitro antibacterial activity against periodontopathogen microorganisms and their stability under different conditions of storage

Type
Research Article
Copyright
Copyright © Materials Research Society 2010

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References

1. Slots, J. The predominant cultivable organisms in juvenile periodontitis. Scand. J. Dent. Res. 84:110 (1976).Google Scholar
2. Slots, J., Mashimo, P., Levine, M. J., and Genco., R. J. Periodontal therapy in humans. I. Microbiological and clinical effects of a single course of periodontal scaling and root planing, and of adjunctive tetracycline therapy. J. Periodontol. 50:495509. (1979).Google Scholar
3. Nisengard and Newman. Oral Microbiology and Immunology. Second Edition. (W. B. Saunders Company, 1994).Google Scholar
4. Kurita, K. Chemistry and Application of Chitin and Chitosan. Polym. Degrad. Stabil. 59: 117120 (1998).Google Scholar
5. Leung, S-HS, Leone, RS, Kumar, LD, Kulkarni, N. Fast dissolving orally consumable films. PCT International Application. WO 00/18365. (2000).Google Scholar
6. Yuen, S., Pullulan and its applications. Process Biochemistry, 9, 710 (1974).Google Scholar
7. Tsujisaka, Y., and Mitsuhashi, M. Pullulan. In “Industrial Gums, Polysaccharides and Their Derivatives” Third Ed., eds. Whistler, R. L., and BeMiller, J. N. (Academic Press, San Diego, 1993) pp. 447460.Google Scholar
8. Kimoto, T, Shibuya, T, Shiobara, S. Safety studies of a novel starch, pullulan: chronic toxicity in rats and bacterial mutagenicity. Food Chem Toxicol. 35:323329. (1997).Google Scholar
9. Alonso, J. Tratado de fitofármacos y neutracéuticos. 1a. Reimpresión corregida y renovada. (Corpus Editorial y Distribuidora, 2007).Google Scholar
10. Rodríguez, García A, Galán, Wong LJ, Rojas, Verde G, Arévalo, Niño K. 2010. Antimicrobial activity of Thymus vulgaris, Matricaria chamomilla, Croton lechleri, Calendula officinalis L., Juliana adstringens Schl. against periodontophatogen microorganisms. Microorganisms in Industry and Environment. From scientific and industrial research to consumer products. (World Scientific Pub. Co. 2010) (in press) pp. 463467.Google Scholar
11. Zheng, LY, Zhu, JF. Study on antimicrobial activity of chitosan with different molecular weights. Carbohydr Polym. 54:527530 (2003).Google Scholar