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Published online by Cambridge University Press: 11 February 2011
The primary deflection due to the chemical reaction between the analyte molecules and the receptor coating, which produces surface stresses on the receptor side is analyzed. The resonance frequency of microcantilevers is very sensitive to the properties of the microcantilever surface. Biosensing experiments based on resonance frequency shift are presented, which show that the results strongly depend on the interaction of specific analyte molecules with the receptor surface.