Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-27T02:17:34.705Z Has data issue: false hasContentIssue false
  • English
  • Français

Covalently-linked Adducts of Single-walled Nanotubes with Biomolecules: Synthesis, Hybridization, and Biologically-Directed Surface Assembly

Published online by Cambridge University Press:  11 February 2011

Sarah E. Baker ,
Tami L. Lasseter ,
Lloyd M. Smith  and
Robert J. Hamers
Sarah E. Baker
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706
Tami L. Lasseter
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706
Lloyd M. Smith
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706
Robert J. Hamers
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706
Get access

Abstract

Covalently-linked adducts of single-walled carbon nanotubes (SWNTs) with biomolecules have been fabricated. Results are presented here for DNA-SWNT and for biotin-SWNT adducts. DNA-SWNT adducts are shown to be biochemically accessible and to exhibit high selectivity, favoring hybridization with complementary vs. non-complementary DNA sequences. Biotin-SWNT adducts were also prepared and used to direct the assembly of nanotubes onto a biotinylated glass surface.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 761: Symposia B/C/D/F/G/NN – Molecular Electronics , 2002 , F4.6
Copyright
Copyright © Materials Research Society 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

[1] Elghanian, R.; Storhoff, J. J.; Mucic, R. C.; Letsinger, R. L.; Mirkin, C. A. Science, 277, 1078, (1997).Google Scholar
[2] Perez, J. M.; O'Loughin, T.; Simeone, F. J.; Weissleder, R.; Josephson, L. J. Am. Chem. Soc., 124, 2856 (2002).Google Scholar
[3] Tsang, S. C.; Guo, Z.; Chen, Y. K.; Green, M. L. H.; Hill, H. A. O.; Hambley, T. W.; Sadler, P. J. Angew. Chem. Int. Ed. Engl., 36, 2198 (1998).Google Scholar
[4] Guo, Z.; Sadler, P. J.; Tsang, S. C. Adv. Mater., 10, 701 (1998).Google Scholar
[5] Chen, R. J.; Zhang, Y.; Wang, D.; Dai, H. J. Am. Chem. Soc., 123, 3838 (2001).Google Scholar
[6] Shim, M.; Kam, N. W. S.; Chen, R. J.; Li., Y.; Dai, H. Nano Letters, 2, 285 (2002).Google Scholar
[7] Baker, S. E.; Cai, W.; Lasseter, T. L.; Weidkamp, K. P.; Hamers, R. J. Nano Letters, 2, 1413 (2002).).Google Scholar
[8] Lasseter, T. L.; Baker, S. E.; Smith, L. M.; Hamers, R. J. In preparation (2002).Google Scholar
[9] Zhao, W.; Song, C.; Pehrsson, P. E. J. Am. Chem. Soc., 124, 12418 (2002).Google Scholar
[10] Strother, T.; Cai, W.; Zhao, X.; Hamers, R. J.; Smith, L. M. J. Am. Chem. Soc., 122 1205–1209 (2000).Google Scholar