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Controlled Release of Natural Polyphenols in Oral Cavity Using Starch Pickering Emulsion

Published online by Cambridge University Press:  19 May 2014

Min S. Wang
Affiliation:
Food Science and Technology Department, University of California Davis, Davis, CA 95616 U.S.A.
Amol Chaudhari
Affiliation:
Food Science and Technology Department, University of California Davis, Davis, CA 95616 U.S.A.
Yuanjie Pan
Affiliation:
Food Science and Technology Department, University of California Davis, Davis, CA 95616 U.S.A.
Stephen Young
Affiliation:
Food Science and Technology Department, University of California Davis, Davis, CA 95616 U.S.A.
Nitin Nitin*
Affiliation:
Food Science and Technology Department, University of California Davis, Davis, CA 95616 U.S.A. Department of Biological and Agricultural Engineering, University of California Davis, Davis, CA 95616 U.S.A.
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Abstract

The goal of this study was to determine the potential use of starch Pickering emulsion as a vehicle to deliver a natural phenolic compound, curcumin in the oral cavity. To this end, an oil-in-water (o/w) emulsion was prepared using starch molecules as the stabilizer/emulsifier. The physical stability, oxygen permeability and release of curcumin from the starch Pickering emulsion in simulated saliva fluid (SSF) were determined. The results of this study showed that the starch stabilized o/w emulsions were stable for up to 2 weeks. The starch Pickering emulsion also provided better protection against oxidation than a surfactant-stabilized emulsion, and the digestion of the starch Pickering emulsion using amylase led to the complete disruption and phase separation of the emulsion.

Type
Articles
Copyright
Copyright © Materials Research Society 2014 

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References

REFERENCES

Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B., Bioavailability of curcumin: problems and promises. Molecular pharmaceutics 2007, 4, (6), 807818.CrossRefGoogle ScholarPubMed
Marku, D.; Wahlgren, M.; Rayner, M.; Sjöö, M.; Timgren, A., Characterization of starch Pickering emulsions for potential applications in topical formulations. International journal of pharmaceutics 2012, 428, (1), 17.Google ScholarPubMed
Tan, Y.; Xu, K.; Liu, C.; Li, Y.; Lu, C.; Wang, P., Fabrication of starch-based nanospheres to stabilize pickering emulsion. Carbohydrate Polymers 2012, 88, (4), 13581363.CrossRefGoogle Scholar
Tikekar, R. V.; Johnson, A.; Nitin, N., Real-time measurement of oxygen transport across an oil–water emulsion interface. Journal of food engineering 2011, 103, (1), 1420.CrossRefGoogle Scholar