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Collagen as a Biomaterial: An Application in Knee Meniscal Fibrocartilage Regeneration

Published online by Cambridge University Press:  15 February 2011

Shu-Tung Li ,
Debbie Yuen ,
Peggy C. Li ,
William G. Rodkey  and
Kevin R. Stone
Shu-Tung Li
Affiliation:
ReGen Biologics, Inc., Franklin Lakes, NJ
Debbie Yuen
Affiliation:
ReGen Biologics, Inc., Franklin Lakes, NJ
Peggy C. Li
Affiliation:
ReGen Biologics, Inc., Franklin Lakes, NJ
William G. Rodkey
Affiliation:
Vail, CO
Kevin R. Stone
Affiliation:
San Francisco, CA USA
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Abstract

Fibrous type I collagen possesses unique physicochemical, mechanical and biological properties which are useful for biomedical applications. Our research in applying collagen materials for various tissue repair has led to the development of a resorbable collagen based implant for meniscal tissue regeneration applications. We discuss here the design and development of this resorbable collagen based implant. The results of safety and efficacy studies indicate that the collagen based implant, if designed properly, can be a safe and effective template to support meniscal tissue regeneration in the knee joint.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 331: Symposium T – Biomaterials for Drug and Cell Delivery , 1993 , 25
Copyright
Copyright © Materials Research Society 1994

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