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Bioactive Materials

Published online by Cambridge University Press:  22 February 2011

L. L. Hench
Affiliation:
Bioglass® Research Center, Box J-413 JHMHC, University of Florida, Gainesville, Florida, 32610, USA
June Wilson
Affiliation:
Bioglass® Research Center, Box J-413 JHMHC, University of Florida, Gainesville, Florida, 32610, USA
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Abstract

Biomaterials can be classified in terms of their interfacial response with tissues: 1) nearly inert, 2) nearly inert microporous, 3) resorbable, and 4) surface active. Surface active biomaterials include bioactive glasses such as Bioglass®, bioactive glass-ceramics such as Ceravital® or A/W Glass-Ceramic, hydroxylapatite such as Calcitite® or bioactive composites such as Palavital® or stainless steel fiber reinforced Bioglass®. All of the above surface active biomaterials form an interfacial bond with adjacent tissue. However, the time dependence of bonding, strength of bond, mechanisms of bonding, and thickness of bonding zone differ. Depending upon composition, type of tissue, and type of load applied, and explanation for the compositional dependence is presented together with various medical and dental implant applications, including middle ear prostheses, maxillofacial reconstruction, endosseous ridge maintenance and augmentation, periodontal packing, and fixation of orthopedic joint prostheses.

Type
Research Article
Copyright
Copyright © Materials Research Society 1986

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References

REFERENCES

1. Hench, L.L., Science 208 826831 (1980).Google Scholar
2. Hench, L.L. and Ethridge, E.C., Biomaterials: An Interfacial Approach, (Academic Press, New York, 1982).Google Scholar
3. Hench, L.L. and Wilson, J. in Silicon Biochemistry, Ciba Foundation Symposium #121. To be published in 1986.Google Scholar
4. Hench, L.L., Splinter, R.J., Greenlee, T.K. and Allen, W.C., J. Biomed. Mats. Res. 2:1 117141, (1971).CrossRefGoogle Scholar
5. Wilson, J., Pigott, G.H., Schoen, F.J. and Hench, L.L., J. Biomed. Mats. Res. 15 805817 (1981).CrossRefGoogle Scholar
6. Greenlee, T.K. Jr, Beckham, C.A., Crebo, A.R. and Malmborg, J.C., J. Biomed. Mater. Res. 6 235244 (1972)Google Scholar
7. Gross, U.M. and Strunz, V., Clinical Applications of Biomaterials, edited by Lee, A.J.C., Albrektsson, T., Branemark, P.I., (Wiley, New York 1982), p. 237.Google Scholar
8. Nakamura, Takashi, Yamamuro, T., Higushi, S., Kakubo, T. and Ito, S., J. Biomed. Mats. Res. (1985).Google Scholar
9. Hohland, W., Naumann, K., Vogel, W., Gummel, J., Jena Math. Naturwiss. Reihe 32 571 (1983).Google Scholar
10. Hench, L.L., 1983 de Physique Colloque C9, Supplement Au No. 12, Tome 43, December 1982, 625–636.Google Scholar
11. Hench, L.L. and Clark, A.E., Biocompatibility of Orthopaedic Implants edited by Williams, D.F. (CRC Press 1982) 2 Chapt. 6.Google Scholar
12. Piotrowski, G., Hench, L.L., Allen, W.C. and Miller, G.J., J. Biomed. Mater. Res., 9 [6] 4761, (1975).Google Scholar
13. Jarcho, M., Clin. Orthop. Relat. Res. 157 259 (1981).Google Scholar
14. Dennissen, H., Mangano, C., Venini, G., Hydroxlapatite Implants, (Piccin Nuova Libraria SPA Padua, Italy 1985).Google Scholar
15. Ogiso, M. et al. , J. Dent. Res. 60A 419 (1981).Google Scholar
16. Hench, L.L. and Wilson, J., Science 226, 630636 (1984).Google Scholar
17. Wilson, June, Merwin, G.E. and Hench, L.L., J. SAMPE 21–3 68 (1985).Google Scholar