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a-Si:H Electrolyte-Gate Thin Film Devices for Biological Applications

Published online by Cambridge University Press:  01 February 2011

Dina Goncalves ,
Duarte M.F. Prazeres ,
Virginia Chu  and
Joao P. Conde
Dina Goncalves
Affiliation:
[email protected], INESC-MN, -, Rua Alves Redol, 9, Lisbon, 1000-029, Portugal
Duarte M.F. Prazeres
Affiliation:
[email protected], Instituto Superior Tecnico, Center of Biological and Chemical Engineering, Av. Rovisco Pais, Lisbon, N/A, 1049-001, Portugal
Virginia Chu
Affiliation:
[email protected], INESC-MN, Rua Alves Redol, 9, Lisbon, N/A, 1000-029, Portugal
Joao P. Conde
Affiliation:
[email protected], INESC-MN, Rua Alves Redol, 9, Lisbon, N/A, 1000-029, Portugal
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Abstract

This paper presents the use of a-Si:H electrolyte-gate thin film transistors (EG-TFTs) for the pH sensing and the detection of DNA and proteins (horseradish peroxidase, HRP). The sensing layer used was SiNx or SiO2. The devices show linear sensitivity to pH above the point of zero charge and respond to the adsorption of oligonuleotides and HRP with typical Langmuir adsorption behavior. DNA immobilization and hybridization detection is demonstrated. Surface control and reproducibility issues are addressed by the measurement of surface contact angles.

Keywords

amorphousbiologicalsensor
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 926: Symposium CC – Electrobiological Interfaces on Soft Substrates , 2006 , 0926-CC08-02
Copyright
Copyright © Materials Research Society 2006

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References

1. Bergveld, P., In: Proceedings of IEEE Sensor Conference, Toronto, 1 (2003).Google Scholar
2.See for example Street, R.A., MRS Bulletin (November), 70 (1992).Google Scholar
3. Gotoh, M., Oda, S., Shimizu, I., Seki, A., Tamiya, E. and Karube, I., Sensors and Actuators 16, 55 (1989).Google Scholar
4. Gleskova, H. and Wagner, S., IEEE Electron Device Letters 20(9), 473 (1999).Google Scholar
5. Conde, J.P., Alpuim, P., Chu, V., Thin Solid Films 430, 240 (2003).Google Scholar
6. Fixe, F., Branz, H.M., Louro, N., Chu, V., Prazeres, D.M.F. and Conde, J.P., Biosensors and Bioelectronics 19, 1591 (2004).Google Scholar
7. Carré, A., Lacarrière, V. and Birch, W., Journal of Colloid and Interface Science 260, 49 (2003).Google Scholar
8. Poghossian, A., Cherstvy, A., Ingebrandt, S., Offenhäusser, A. and Schöning, M.J., Sensors and Actuators B 111–112, 470 (2005).Google Scholar