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Amine-rich Polyelectrolyte Adhesion Layers as an Alternative to APTES for Surface Immobilization of Biomolecules and Nanostructures
Published online by Cambridge University Press: 30 August 2011
Abstract
We propose the use of amine-rich polyelectrolyte multilayers as a versatile, high quality, tunable adhesive surfaces for biomedical and nanotechnological applications. The films are simple to fabricate under mild conditions and provide at least as good adhesion as standard aminopropyltriethoxysilane terminated glass substrates. In addition, the multilayer surface can be reliably passivated by acetylation with acetic anhydride which reduces the adhesion to the point that non-specific binding of proteins and nanoparticles becomes all but negligible. We demonstrate that this property, in combination with the robustness of the film, makes it possible to pattern the adhesiveness of the film at the nanoscale level.
Keywords
- Type
- Research Article
- Information
- MRS Online Proceedings Library (OPL) , Volume 1355: Symposium JJ – Biological Hybrid Materials for Life Sciences , 2011 , mrss11-1355-jj03-11
- Copyright
- Copyright © Materials Research Society 2011