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Thin Film Phosphate Based Bioactive Substrates

Published online by Cambridge University Press:  15 February 2011

S Langstaff
Affiliation:
Queen's University, Department of Physics, Kingston, ON K7L 3N6
M Sayer
Affiliation:
Queen's University, Department of Physics, Kingston, ON K7L 3N6
L Weaver
Affiliation:
Queen's University, Department of Physics, Kingston, ON K7L 3N6
S Pugh
Affiliation:
Millenium Biologix Inc., 785 Midpark Dr., Suite 200, Kingston, ON K7M 7G3
T Smith
Affiliation:
Millenium Biologix Inc., 785 Midpark Dr., Suite 200, Kingston, ON K7M 7G3
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Abstract

Calcium phosphate based thin films prepared by colloidal sol-gel slow draw dipping of quartz substrates are bioactive to both osteoclast resorption and osteoblast deposition. The bioactivity is related to the presence of mixed crystalline phases in the films generated under different sintering conditions. As the sintering temperature was increased from 800°C to 1000°C, a transition in film composition from calcium hydroxylapatite to alpha-tricalcium phosphate is achieved.

Type
Research Article
Copyright
Copyright © Materials Research Society 1996

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References

1. Tofe, A.J., Brewster, G.A. and Bowerman, M.A. in Characterization and Performance of Calcium Phosphate Coatings for Implants, edited by Horowitz, E. and Parr, J.E. (ASTM PCN: 04-011960-54, Philadelphia, PA 1994) p. 917.Google Scholar
2. Davies, J.E., Shapiro, G. and Lowenberg, B.F., Cells and Materials. 3(3), p. 245256 (1993).Google Scholar
3. Qui, Q., Vincent, P., Lowenberg, B., Sayer, M. and Davies, J.E., Cells and Materials. 3(4) p. 351360 (1993)Google Scholar