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Targeting Magnetic Nanoparticles in High Magnetic Fields for Drug Delivery Purposes

Published online by Cambridge University Press:  15 March 2011

Ramazan Asmatulu ,
Richard.O. Claus ,
Judy S. Riffle  and
Michael Zalich
Ramazan Asmatulu
Affiliation:
Fiber & Electro Optics Research Center, Bradley Department of Electrical and Computer Engineering, Virginia Tech, 106 Plantation Road, Blacksburg, VA 24061
Richard.O. Claus
Affiliation:
Fiber & Electro Optics Research Center, Bradley Department of Electrical and Computer Engineering, Virginia Tech, 106 Plantation Road, Blacksburg, VA 24061
Judy S. Riffle
Affiliation:
Department of Chemistry, Virginia Tech, 2018 Hahn Hall, Blacksburg, VA 24061
Michael Zalich
Affiliation:
Department of Chemistry, Virginia Tech, 2018 Hahn Hall, Blacksburg, VA 24061
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Abstract

Biodegradable magnetic nanoparticles were synthesized using Poly(L-Lactic Acid) and magnetite nanoparticles (∼14 nm) at different dosages, and then these nanaoparticles (nanocomposites) and pure magnetic particles were targeted in external magnetic fields by changing the test parameters. The magnetic field test results showed that magnetic saturation, fluid speed, magnetic field distance and particle size were extremely effective for a magnetic guidance system that is needed for an effective drug delivery approach. Thus, it is assumed that such nanoparticles can carry drugs (chemotherapy) to be able to cure cancer tumors as well as many other diseases.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 820: Symposia O/R – Nanoengineered Assemblies and Advanced Micro/Nanosystems , 2004 , O3.8
Copyright
Copyright © Materials Research Society 2004

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